INTRODUCTION ABOUT JALRA-M 50/500 MG TABLET

JALRA-M 50/500 MG TABLET is used to manage type 2 diabetes (non-insulin-dependent diabetes mellitus) in adult patients whose diabetes cannot be controlled by diet and exercise alone and/or with other medicines used to manage diabetes (insulin or sulphonylureas such as glimepiride and glipizide). It is a combination of Metformin and Vildagliptin which belongs to a group of medicines called Antidiabetic agents.

Before taking JALRA-M 50/500 MG TABLET, inform your doctor if you have liver, kidney, or heart problems. It should be used during pregnancy only if advised by your doctor, and it is not recommended for pregnant women. JALRA-M 50/500 MG TABLET is not suitable for use in children and adolescents under 18 years of age, and it should be used with caution in elderly patients (65 years of age and above).

Avoid consumption of alcohol during management with JALRA-M 50/500 MG TABLET, as it may increase the risk of lactic acidosis. The most common side effects of taking JALRA-M 50/500 MG TABLET are stomach pain, low blood sugar, and diarrhea. Contact your doctor if any of the symptoms worsen.

USES OF JALRA-M 50/500 MG TABLET

• Used to manage type II diabetes mellitus (whose diabetes cannot be controlled by diet and exercise alone and/or with other medicines used to manage diabetes)

HOW JALRA-M 50/500 MG TABLET WORKS

JALRA-M 50/500 MG TABLET helps to control the blood sugar level, where Metformin makes the body more sensitive to insulin (a hormone involved in glucose metabolism). This helps our body cells utilize more of the circulating blood glucose. Additionally, it can stop glucose production by the liver and reduce its absorption in the body. Vildagliptin controls blood sugar levels by blocking the actions of an enzyme called dipeptidyl peptidase (DPP)-4 that indirectly increases insulin secretion in the body. Collectively, JALRA-M 50/500 MG TABLET controls blood sugar levels in patients with type II diabetes.

DIRECTIONS FOR USE

• Take JALRA-M 50/500 MG TABLET as directed by your physician
• Swallow the medicine as a whole and do not crush or chew the medicine
• Your doctor will decide the correct dose and duration for you, depending on your age and health condition
• Do not stop taking JALRA-M 50/500 MG TABLET without informing your doctor

SIDE EFFECTS OF JALRA-M 50/500 MG TABLET

Common Side Effects of JALRA-M 50/500 MG TABLET:

• diarrhea
• stomach pain
• loss of appetite
• metallic taste
• low blood glucose
• joint pain, tiredness
• constipation
• swollen hands, ankles, or feet (oedema)

Stop taking JALRA-M 50/500 MG TABLET and contact your doctor immediately if you experience any of the following side effects:

• symptoms of lactic acidosis (such as vomiting, stomach pain, decreased heartbeat, difficulty breathing, muscle cramps, general weakness with severe tiredness, or reduced body temperature)
• signs of an inflamed pancreas (severe and persistent pain in the abdomen with or without nausea or vomiting)

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking JALRA-M 50/500 MG TABLET, inform your doctor if you are taking any of these medicines:

• Glucocorticoids (Ex. dexamethasone and prednisolone)
• Beta-2 agonists (Ex. albuterol and terbutaline) 
• Diuretics (Ex. chlorthalidone and hydrochlorothiazide)
• NSAID’s (Ex. Ibuprofen and celecoxib)
• Angiotensin-converting enzyme (ACE) inhibitors (Ex. enalapril, lisinopril)
• Angiotensin II receptor antagonists (Ex. losartan, telmisartan)
• Antidiabetics (Ex. glimepiride, glipizide)
• Anti-anginal (Ex. Ranolazine)
• Anti-viral agents (Ex. Dolutegravir)
• Kinase inhibitors (Ex. Vandetanib)
• H2 blockers (Ex. Cimetidine)

Overdosage:

If you or anyone else accidentally takes too much of JALRA-M 50/500 MG TABLET, consult your doctor immediately. Overdosage symptoms of JALRA-M 50/500 MG TABLET might include low blood sugar levels, lactic acidosis, muscle pain, mild and transient burning or tickling sensations in the body, fever, and oedema.

SYNOPSIS