INTRODUCTION ABOUT DYNAGLIPT M TABLET

DYNAGLIPT M TABLET is used to manage high blood sugar levels in people with type 2 diabetes mellitus. It is a combination of Metformin and Teneligliptin which belongs to the group of medicines called Antidiabetic agents.

Before taking DYNAGLIPT M TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have low potassium levels in blood or are severely dehydrated due to excessive vomiting or diarrhea recently. During therapy with DYNAGLIPT M TABLET, your doctor might regularly monitor blood sugar levels and kidney functions to avoid the risk of unwanted side effects.

DYNAGLIPT M TABLET is not recommended for use in patients with severe uncontrollable diabetes. It is also not suitable for use in patients with alcoholism and in patients with severe systemic infections. The most common side effects of taking DYNAGLIPT M TABLET are low blood sugar levels, stomach upset, constipation, flatulence and altered taste sensations. Consult your doctor if any of the above side effects bother you.

USES OF DYNAGLIPT M TABLET

• Used to manage type II diabetes mellitus

HOW DYNAGLIPT M TABLET WORKS

DYNAGLIPT M TABLET contains Metformin and Teneligliptin. Metformin works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body’s sensitivity to insulin. Teneligliptin is a dipeptidyl peptidase-4 inhibitor which works by increasing the release of insulin from pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and post-meal sugar levels. Together, they provide better control of blood sugar.

DIRECTIONS FOR USE

• Take DYNAGLIPT M TABLET preferably after meals or as advised by your physician
• Swallow the medicine with a glass of water. Do not crush or chew the medicine
• Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition
• Do not stop taking DYNAGLIPT M TABLET unless your doctor advice you to stop

SIDE EFFECTS OF DYNAGLIPT M TABLET

Common side effects of DYNAGLIPT M TABLET:

• hypoglycemia  
• flatulence, diarrhea, constipation, stomach pain, loss of appetite
• changes in taste

Stop taking DYNAGLIPT M TABLET and consult your doctor immediately if you experience any of the following side effects:

• serious allergic reaction (hives, swelling of the face, lips, tongue or throat causing difficulty in breathing or swallowing)
• severe skin rashes with redness and blistering of the skin
• signs of lactic acidosis (cold hands or feet, dizziness or light-headedness, slow or irregular heartbeat, weakness or tiredness, unusual muscle pain, trouble breathing, sleepiness or drowsiness, stomach pains, nausea or vomiting)
• signs of liver damage (tiredness, loss of appetite, weight loss, with or without yellowing of the skin or whites of the eyes)

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking DYNAGLIPT M TABLET, inform your doctor if you are taking any of the following medicines such as:

• Anti-diabetics (Ex. glimepiride, glyburide, gliclazide, rosiglitazone, pioglitazone)
• iodine contrast medium (used during X-rays)
• Bronchodilators (Ex. salbutamol or terbutaline)
• Corticosteroids (Ex. hydrocortisone, prednisolone)
• diuretics (Ex. furosemide, hydrochlorothiazide)
• Non-steroidal anti-inflammatory agents (Ex. ibuprofen and celecoxib)
• Antihypertensives (such as atenolol, propranolol, captopril, enalapril, ramipril, lisinopril, losartan, valsartan, olmesartan, telmisartan)
• H2 blockers (Ex. cimetidine)
• Anti-viral agents (Ex. dolutegravir)
• Calcium-channel blockers (Ex. verapamil)
• Antimicrobial (Ex. rifampicin)
• Anti-anginals (Ex. ranolazine)
• Antibiotics (Ex. trimethoprim)
• Anti-cancer agents (Ex. vandetanib, crizotinib and Olaparib)
• Anti-fungal (Ex. isavuconazole)
• Keratolytic agents (Ex. salicylic acid)
• Antidepressants (Ex. phenelzine, selegiline)
• Sympathomimetic agents (Ex. adrenaline)
• Thyroid hormones (Ex. levothyroxine, liothyronine)
• Cardiac glycosides (Ex. quinidine, procainamide, amiodarone, sotalol)

Overdosage:

If you or anyone else accidentally took more of  DYNAGLIPT M TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are feeling cold, severe nausea or vomiting, stomach pain, unexplained weight loss, muscular cramps and fast breathing.

SYNOPSIS