INTRODUCTION ABOUT DOLOWIN PLUS TABLET

DOLOWIN PLUS TABLET is used for pain management associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It can also be used to reduce pain caused due to sprains, strains, sports injuries, tendon pain, bone fracture pain and minor surgical and other pains. It is a combination of Aceclofenac + Paracetamol which are pain relieving agents.

Take DOLOWIN PLUS TABLET after food to avoid gastric irritation. Do not take this medicine more than the duration recommended by your doctor. Before taking this medicine inform your doctor if you are having any liver, kidney or heart problems. You must also inform your doctor if you have stomach ulcers, gut inflammation, inflammatory bowel diseases or chronic alcoholism, or if you are pregnant or breastfeeding as a precaution.

The most common side effects of taking DOLOWIN PLUS TABLET are indigestion, stomach pain, bloating and headache which can be managed by taking this medicine with meals and by following simple diet with less spicy food and limiting alcohol consumption.

USES OF DOLOWIN PLUS TABLET

Pain management associated with inflammatory bowel conditions:

• Osteoarthritis
• Rheumatoid arthritis
• Ankylosing spondylitis
• Sprains, Strains, tendon pain, bone fracture pain
• Minor surgical and other pains

HOW DOLOWIN PLUS TABLET WORKS

DOLOWIN PLUS TABLET contains aceclofenac and paracetamol which works together to relieve pain and inflammation. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that blocks enzymes called cyclooxygenase (COX) enzymes, reducing the production of chemicals called prostaglandins, which are responsible for causing pain and inflammation.

Paracetamol, on the other hand, works by reducing the perception of pain in the brain and also helps lower fever by acting on the heat-regulating centers in the brain. Together, they provide stronger pain relief and reduce inflammation.

DIRECTIONS FOR USE

• DOLOWIN PLUS TABLET should be taken as directed by your doctor.
• Typically, they are taken orally with water, preferably after food to avoid stomach upset.
• The usual dose is one tablet 1-2 times a day, depending on the condition being treated and your doctor's instructions.
• Do not exceed the prescribed dose, and follow the timing as recommended for the best results.
• Always consult your doctor for personalized advice on dosage and duration.

SIDE EFFECTS OF DOLOWIN PLUS TABLET

Common Side Effects of DOLOWIN PLUS TABLET:

• Indigestion, abdominal pain, nausea, constipation
• headache
• dizziness
• drowsiness
• mouth ulcers

Stop taking DOLOWIN PLUS TABLET and consult your doctor immediately if you experience any of the following side effects:

• gastrointestinal ulceration and bleeding
• signs of low blood sugar

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking DOLOWIN PLUS TABLET, inform your doctor if you are taking any of the following medicine:

• other analgesics such as aspirin, cyclooxygenase-2 selective inhibitors (Ex. celecoxib, valdecoxib)
• anti-hypertensives (Ex. atenolol, propranolol)
• diuretics (Ex. hydrochlorothiazide, furosemide)
• cardiac glycosides (Ex. digoxin, digitoxin)
• lithium (medicine used to manage depression)
• methotrexate (medicine used to manage cancer)
• mifepristone (used for abortion)
• corticosteroids (Ex. prednisone, dexamethasone)
• anti-coagulants (Ex. Warfarin)
• quinolone antibiotics (Ex. ciprofloxacin, levofloxacin)
• antiplatelets (Ex. Warfarin)
• Antidepressants (such as citalopram, dapoxetine, escitalopram, fluoxetine)
• cyclosporin (used to manage organ rejection after transplantation)
• tacrolimus (used to manage moderate to severe atopic dermatitis)
• zidovudine (used to manage HIV)
• anti-diabetic agents (such as glipizide, glyburide)
• cholestyramine (used to manage high cholesterol level)
• metoclopramide, domperidone (used to manage nausea and vomiting)
• chloramphenicol (used to manage serious bacterial infections)

Overdosage:

If you or anyone else accidentally takes too much of DOLOWIN PLUS TABLET, consult your doctor immediately.

SYNOPSIS