INTRODUCTION ABOUT DEPLATT CV 20MG CAPSULE

DEPLATT CV 20MG CAPSULE is a combination of Aspirin, Clopidogrel and Atorvastatin which belongs to the group of medicines called Antiplatelets and HMG-CoA reductase inhibitors respectively. DEPLATT CV 20MG CAPSULE is indicated in the management of patients with percutaneous coronary intervention (PCI) and myocardial infarction (also known as heart attack which occurs when blood flow to the heart muscle is blocked or interrupted).

Percutaneous coronary intervention (also known as angioplasty with stent) is a non-surgical procedure used among patients with heart problems (such as cardiogenic shock, acute severe heart failure or ischemic symptoms) to unclog blood vessels in the heart that have been narrowed by plaque buildup by placing a stent.        

Along management with DEPLATT CV 20MG CAPSULE follow a healthy low-fat diet as advised by your doctor to achieve better results. Avoid drinking alcohol during management with DEPLATT CV 20MG CAPSULE, as it could increase the risk of bleeding in the gastrointestinal tract.    

DEPLATT CV 20MG CAPSULE is not recommended for use in patients with severe liver or kidney disease, recent ischemic stroke, gout, active or recurrent peptic ulcer with or without gastrointestinal bleeding and bleeding disorders (such as bleeding in the brain or hemophilia).

DEPLATT CV 20MG CAPSULE is generally not recommended for use in pregnant or breastfeeding women and in children or adolescents (aged below 18 years). It should be used with caution in elderly patients (aged 70 years or above) because of increased risk of gastro-intestinal bleeding.

The most common side effects of taking DEPLATT CV 20MG CAPSULE are increased bleeding tendency, nausea, indigestion, diarrhea, stomach pain, constipation, muscle pain, dizziness and headache. Consult your doctor if any of these side effects worsen.  

USES OF DEPLATT CV 20MG CAPSULE

• Manage patients with percutaneous coronary intervention (PCI) and myocardial infarction

HOW DEPLATT CV 20MG CAPSULE WORKS

DEPLATT CV 20MG CAPSULE effectively improves cardiac function and reduces the risk of heart problems, where clopidogrel acts by inhibiting platelet aggregation in the coronary arteries, aspirin acts by blocking the actions of an enzyme called cyclo-oxygenase 1 which is believed to be responsible for catalyzing the synthesis of platelets and atorvastatin acts by inhibiting the action of an enzyme called HMG-CoA reductase, which is required to catalyze the formation of cholesterol, thus managing clot or plaque formation in the coronary arteries leading to an uninterrupted supply of oxygen and blood to the heart.

DIRECTIONS FOR USE

Take DEPLATT CV 20MG CAPSULE as advised by your physician. Swallow DEPLATT CV 20MG CAPSULE with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF DEPLATT CV 20MG CAPSULE

HOW TO MANAGE SIDE EFFECTS

Nausea:

Try to take DEPLATT CV 20MG CAPSULE with or just after a meal or a snack. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if the symptom does not improve.

Diarrhea:

Drink lot of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for managing diarrhea. Consult your doctor if the symptom does not improve.

Headache:  

Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the forehead if required. Do not consume too much of alcohol. Consult your doctor if the symptom does not improve.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom does not improve.

Constipation: 

Eat fiber rich foods such as fresh fruits, vegetables, cereals and drink plenty of water. Try to exercise more regularly. Consult your doctor if the symptom does not improve.

Stomach pain:

Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. Do not self-manage on your own and consult your doctor if the symptom does not improve.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking DEPLATT CV 20MG CAPSULE inform to your doctor, if you are taking any of these medicines:

• other anticoagulants (used for blood thinning) Ex. warfarin, coumarin, heparin, phenindione
• other cholesterol-lowering medicines (Ex. clofibrate, gemfibrozil, fenofibrate, ezetimibe, colestipol)
• other non-steroidal anti-inflammatory drugs (Ex. ibuprofen, indomethacin)
• medicines used to manage HIV infection (Ex. glecaprevir/pibrentasvir, delavirdine, ritonavir with lopinavir and/or atazanavir or sofosbuvir with velpatasvir and voxilaprevir)
• st. john's wort (herbal medicine), selective serotonin reuptake inhibitors (used to manage depression) Ex. fluoxetine, sertraline, paroxetine or fluvoxamine 
• medicines used to manage stomach ulcers such as antacids (Ex. aluminium hydroxide, magnesium hydroxide) and proton-pump inhibitors (Ex. omeprazole or esomeprazole)
• other medicines used during percutaneous coronary intervention (Ex. abciximab, eptifibatide and tirofiban)
• antibiotics (used to manage bacterial infections) such as macrolides (Ex. azithromycin, telithromycin, erythromycin, roxithromycin, and clarithromycin) or fusidic acid
• medicines used to manage epilepsy (Ex. phenytoin, valproic acid, stiripentol)
• medicines used to manage diabetes (Ex. insulin, glipizide, glimepiride)
• ciclosporin or tacrolimus (used to manage graft rejection or manage auto-immune disease)
• azole antifungal agents (used to manage fungal infection) Ex. clotrimazole, fluconazole
• methotrexate (used to manage cancer or other auto-immune diseases)
• lithium (used to manage mental illness)
• corticosteroids (used to manage pain and inflammation) Ex. prednisolone, dexamethasone
• acetazolamide (used to manage or manage altitude sickness)
• mifepristone (used to manage pregnancy)
• metoclopramide (used to manage vomiting)
• deferasirox (used to manage iron overload)
• zafirlukst (used to manage asthmatic symptoms)
• digoxin, amiodarone and verapamil (used to manage abnormal heart rhythm)
• angiotensin-converting enzyme (ACE) inhibitors such as captopril, enalapril and diuretics such as hydrochlorothiazide (used to manage high blood pressure)
• rifampin (used to manage tuberculosis)
• colchicine, probenecid or sulfinpyrazone (used to manage gout)

B. Drug - Food interaction:

During management with DEPLATT CV 20MG CAPSULE, do not take more than one or two small glasses of grapefruit juice per day because large quantities of grapefruit juice can alter the effects of this medicine.

Overdosage:

If you or anyone else accidentally take too much of DEPLATT CV 20MG CAPSULE, contact your doctor immediately or go to a hospital straight away. Overdosage symptoms of DEPLATT CV 20MG CAPSULE includes increased bleeding, confusion, disorientation, coma, convulsions, vomiting (sometimes with blood), increased body temperature, low blood sugar levels, tinnitus (ringing in the ears), vertigo (spinning sensation), sweating, warm extremities with bounding pulses, kidney failure, increased respiratory rate and hyperventilation. 

SYNOPSIS

MORE INFORMATION

• Keep DEPLATT CV 20MG CAPSULE out of reach of children
• Store DEPLATT CV 20MG CAPSULE at room temperature