INTRODUCTION ABOUT DANOGEN 50MG CAPSULE

DANOGEN 50MG CAPSULE contains Danazol which belongs to the group of medicines called Androgens. It is used to manage endometriosis, severe cyclical mastalgia (breast pain associated with hormonal variations), breast cysts, dysfunctional uterine bleeding (bleeding from vagina other than that of menstrual cycle), symptomatic gynecomastia, preoperative thinning of endometrium and hereditary angioneurotic edema (painless swelling under the skin).

Endometriosis is defined as an illness where some of the tissues that line the womb are found elsewhere in the body. Gynecomastia refers to an increase in the amount of breast gland tissue in males, due to an imbalance of hormones estrogen and testosterone.

Prior to the management, your doctor may want you to take several blood tests to understand your existing condition.

Avoid consumption of alcohol during management with DANOGEN 50MG CAPSULE, as it may cause nausea or breathlessness.

Before taking DANOGEN 50MG CAPSULE, inform your doctor if you have hormonal cancer, blood clots, heart, liver or kidney problems or porphyria.

DANOGEN 50MG CAPSULE is not recommended for use among pregnant or breastfeeding women, therefore consult your doctor before taking it.

Safety and effectiveness of DANOGEN 50MG CAPSULE in paediatric and elderly patients have not been established.

The most common side effects of taking DANOGEN 50MG CAPSULE are weight gain, bloating, nausea, vomiting, lethargy and headache. Consult your doctor if any of the side effects worsen.

USES OF DANOGEN 50MG CAPSULE

Manage:

• endometriosis
• severe cyclical mastalgia
• breast cysts
• dysfunctional uterine bleeding
• symptomatic gynecomastia
• preoperative thinning of endometrium
• hereditary angioneurotic edema

HOW DANOGEN 50MG CAPSULE WORKS

DANOGEN 50MG CAPSULE works by suppressing the secretion of gonadotropins (a group hormones that stimulate the activity of the gonads) in both men and women, leading to inhibition of testicular/ovarian function. In addition, it suppresses gonadal function directly by inhibiting the enzymes involved in steroid hormone synthesis.

DIRECTIONS FOR USE

Take DANOGEN 50MG CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop taking DANOGEN 50MG CAPSULE unless your doctor advice you to stop.

SIDE EFFECTS OF DANOGEN 50MG CAPSULE

HOW TO MANAGE SIDE EFFECTS

Headache:

Drink ample amount of water. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.

Nausea:

Take DANOGEN 50MG CAPSULE with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. Consult your doctor if the symptom does not improve.

Vomiting:

Get adequate rest. Drink sufficient amount of fluids, especially water. Have small sips if you feel sick. Eat when you feel hungry. Do not take any medicine for vomiting without asking your doctor. Consult your doctor if the symptom gets worse.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking DANOGEN 50MG CAPSULE, inform your doctor if you are taking any of the following medicines:

• steroids (used in oral contraception and hormone replacement therapy) Ex. testosterone, estrogen, progesterone
• medicines used to lower blood cholesterol levels (Ex. simvastatin, atorvastatin)
• medicines used to manage fits (Ex. phenytoin, carbamazepine)
• medicines used to thin the blood (Ex. warfarin, clopidogrel)
• anaesthetics (used to manage pain during procedures) Ex. midazolam, propofol
• medicines used to stop the rejection of organs after a transplant (Ex. ciclosporin and tacrolimus)
• alpha calcidol (used for vitamin D deficiency and illness where there is lack of calcium in the blood)
• medicines used to lower blood sugar levels (Ex. metformin, glyburide)
• medicines used to manage high blood pressure (Ex. atenolol, diltiazem)
• medicines used to manage migraine (Ex. sumatriptan, rizatriptan)

Overdosage:

If you or anyone else accidentally take too much of DANOGEN 50MG CAPSULE, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep DANOGEN 50MG CAPSULE out of reach of children
• Store at room temperature