INTRODUCTION ABOUT ZYLORIC 300MG TABLET

ZYLORIC 300MG TABLET contains Allopurinol which belongs to a group of medicines called Enzyme inhibitors. It is used to manage gout, kidney stones, enzyme disorders (Lesch-Nyhan Syndrome), and high levels of uric acid caused by certain cancer medications.

Gout is a form of arthritis due to high levels of uric acid in the body and this uric acid builds up in the joints and tendons as crystals causing severe pain, redness and tenderness in joints.

Before taking ZYLORIC 300MG TABLET, inform your doctor if you have kidney or liver problems, high blood pressure or heart problems, thyroid, cancer or Lesch-Nyhan syndrome, gout attack, lactose or galactose intolerance and glucose-galactose malabsorption.

ZYLORIC 300MG TABLET should be used with caution in pregnant women and it is not recommended for use in breastfeeding women as it passes through the breast milk. Consult your doctor before taking it.

ZYLORIC 300MG TABLET is not recommended for use in children below children under 15 years of age except in some types of cancer such as leukaemia and certain enzyme disorders such as Lesch-Nyhan syndrome. ZYLORIC 300MG TABLET should be used with caution in elderly patients above 65years of age. Consult your doctor before taking it.

The most common side effects of taking ZYLORIC 300MG TABLET are skin rash and increased levels of thyroid stimulation hormone in blood. Consult with your doctor if any of these worsens or doesn’t improve.

USES OF ZYLORIC 300MG TABLET

Manages,

• gout
• kidney stones formation
• certain types of kidney diseases
• some types of cancer (especially leukemia)
• Lesch-Nyhan syndrome

HOW ZYLORIC 300MG TABLET WORKS

ZYLORIC 300MG TABLET works by stopping the enzyme (xanthine oxidase) which is responsible for production of uric acid. Thus lowering the levels of uric acid in blood and urine and decreases the incidence of gout symptoms.

DIRECTIONS FOR USE

Take ZYLORIC 300MG TABLET as advised by your physician. Swallow the medicines with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF ZYLORIC 300MG TABLET

HOW TO MANAGE SIDE EFFECTS

Itchy rash:

Avoid hot showers because hot water can irritate the skin. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use moisturizer to soothe and hydrate the affected area. If the symptom does not improve, contact your doctor.

Nausea or vomiting:

Try to take this medicine with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. If the symptom does not improve, contact your doctor.

Diarrhoea:

Drink lots of fluids, such as water or fruit juices to keep you hydrated. Do not take any medicine on your own for managing diarrhea. Contact your doctor if the symptom did not improve.

Stomach pain:

Rest and relax. Eat and drink slowly or try to have smaller meals. Keep a heat pad on your stomach. Do not self-manage and contact your doctor if the symptom did not improve.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug - Drug interactions:

Before taking ZYLORIC 300MG TABLET, inform your doctor if you are taking any of the following medicine:

• aspirin (medicine used to manage heart diseases, pain)
• theophylline (medicine used for asthma and breathing disorders)
• medicines used to manage epilepsy (Ex. phenytoin, carbamazepine).
• vidarabine (used to manage herpes simplex or chicken pox)
• medicines used to manage bacterial infections (Ex. ampicillin and amoxicillin)
• didanosine (used to manage HIV infection)
• medicines used to manage diabetes (Ex. chlorpropamide and tolbutamide)
• cytostatics (medicines stop the cell growth in cancer). Ex. cyclophosphamide, doxorubicin, bleomycin, procarbazine, alkyl halogenides
• azathioprine (medicines used for rheumatoid arthritis and after organ transplants)

• medicines used to manage high blood pressure, heart failure (Ex. captopril)
• medicines used to thin the blood (Ex. dicoumarol, phenprocoumon, and warfarin)
• medicines used to reduce uric acid levels, gout (Ex. probenecid, salicylate).
• aluminium hydroxide (medicines used to manage acidity)

Overdosage:

If you or anyone else accidentally take too much of ZYLORIC 300MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are nausea, vomiting, diarrhoea and dizziness.

SYNOPSIS

MORE INFORMATION

• Keep ZYLORIC 300MG TABLET out of the sight and reach of children
• Store ZYLORIC 300MG TABLET below 25°C