INTRODUCTION ABOUT TRIOLMEZEST 20MG TABLET

TRIOLMEZEST 20MG TABLET is a combination of Amlodipine, Hydrochlorothiazide and Olmesartan which belongs to the group of medicines called Antihypertensive agents. It is used to manage hypertension (high blood pressure) when management with single agents is not effective.

Hypertension (also known as high blood pressure) is a medical condition in which the force of the blood exerted against the walls of the artery remains very high, and as a result it may lead to severe damage to the blood vessels supplying several vital organs, such as heart, kidney, or brain. If left unmanageed, it may cause serious complications such as heart attack, heart failure, stroke or even blindness.

During management with TRIOLMEZEST 20MG TABLET your doctor will constantly monitor your kidney functions, blood pressure, electrolyte levels and blood sugar levels to avoid the risk of unwanted side effects. Avoid eating grapefruit or drinking grapefruit juice while taking TRIOLMEZEST 20MG TABLET as it may severely decrease your blood pressure.

Before taking TRIOLMEZEST 20MG TABLET inform your doctor if you have any heart, liver, or kidney problems. You must also inform your doctor if you have diabetes, low blood pressure or are severely dehydrated due to excessive vomiting or diarrhea.

TRIOLMEZEST 20MG TABLET is also not suitable for use in pregnant or breastfeeding women as it may cause serious harm to the growing baby. Stop taking TRIOLMEZEST 20MG TABLET and inform your doctor immediately if you become pregnant while undergoing therapy with TRIOLMEZEST 20MG TABLET.

The most common side effects of taking TRIOLMEZEST 20MG TABLET are low blood pressure, dizziness, tiredness, headache, sleepiness, muscle cramps and swollen ankles. Contact your doctor if any of these side effect worsens.

USES OF TRIOLMEZEST 20MG TABLET

• Manage Hypertension (high blood pressure)

HOW TRIOLMEZEST 20MG TABLET WORKS

TRIOLMEZEST 20MG TABLET is an antihypertensive medicine. It relaxes your blood vessels and improves blood flow across them. It also reduces thickness of the blood by removing excess fluids from the body in the form of urine. Collectively, these actions reduce the strain on the heart and helps the heart to pump blood more smoothly with less pressure.

DIRECTIONS FOR USE

Take TRIOLMEZEST 20MG TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Try to take TRIOLMEZEST 20MG TABLET at the same time each day. TRIOLMEZEST 20MG TABLET can be taken with or without food.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition.

Continue to take TRIOLMEZEST 20MG TABLET for the stipulated duration instructed by your doctor without any interruption to achieve better results.

SIDE EFFECTS OF TRIOLMEZEST 20MG TABLET

HOW TO MANAGE SIDE EFFECTS

Nausea and vomiting:

Take TRIOLMEZEST 20MG TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

Headache:  

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug - Drug interactions:

• medicines used to manage bacterial infections (Ex. erythromycin, clarithromycin, telithromycin, trimethoprim)
• medicine used to manage HIV infection (Ex. indinavir, ritonavir, saquinavir)
• medicines used to manage fungal infections (Ex. itraconazole, ketoconazole and fluconazole)
• medicines used for heart problems (such as verapamil, diltiazem)
• dantrolene (a medicine used to manage muscle spasms)
• medicines to suppress immune system (Ex. cyclosporin, tacrolimus, sirolimus, temsirolimus and everolimus)
• simvastatin, cholestyramine and colestipol (medicines to lower the cholesterol)
• potassium supplements or potassium-sparing diuretics such as spironolactone, triamterene or amiloride (used to retain or increase potassium levels in the body)
• antidepressants such as lithium, citalopram, fluoxetine, paroxetine, nefazodone, St. John’s wort (herbal medicine used to manage depression)
• other medicines used to manage elevated blood pressure (such as aliskiren, bosentan, methyldopa, guanethidine, captopril, enalapril, lisinopril, verapamil, diltiazem, losartan, valsartan)
• other diuretics (used to reduce edema) Ex. furosemide, bumetanide
• adrenaline or nor-adrenaline (used for low blood pressure, shock, cardiac failure, asthma or allergies)
• medicines used to manage gout (such as probenecid, sulfinpyrazone and allopurinol)
• laxatives (used to manage constipation) Ex. lactulose
• glycyrrhizin (a medicine used to reduce bronchitis)
• anti-diabetic medicines and insulin (used to lower the blood glucose level) Ex. vildagliptin, metformin
• corticosteroids (used to manage inflammation) Ex. prednisolone
• iodinated contrast agents (used during X-ray procedures)
• atropine (a medicine used to improve heart rate)
• biperiden (a medicine used to manage parkinsonism)
• antipsychotics (used to manage serious mental illnesses) Ex. clozapine, risperidone
• medicines used to relieve pain (Ex. morphine, aspirin, diclofenac, diflunisal, celecoxib, valdecoxib)

B. Drug-Food interactions:

Do not eat grapefruit or drink grapefruit juice while taking TRIOLMEZEST 20MG TABLET as it may increase the risk of side effects

Overdosage:

If you or anyone else accidentally took more TRIOLMEZEST 20MG TABLET, consult your doctor immediately. Overdosage may cause low blood pressure, abnormal heartbeat, and dizziness.

SYNOPSIS

MORE INFORMATION

• Keep TRIOLMEZEST 20MG TABLET out of reach of children
• Store TRIOLMEZEST 20MG TABLET at room temperature