INTRODUCTION ABOUT TIGATEL H 40MG TABLET

TIGATEL H 40MG TABLET is used in the management of hypertension. It contains a combination of Hydrochlorothiazide+Telmisartan that works by removing excess fluids from the body and relaxing the blood vessels which reduces strain on the heart and reduces blood pressure.

Take this medicine as advised by your physician. It can be taken with or without food. During management with TIGATEL H 40MG TABLET your doctor will constantly monitor your kidney functions, blood pressure, electrolyte levels and blood sugar levels to avoid the risk of unwanted side effects.

Before taking TIGATEL H 40MG TABLET inform your doctor if you have any heart, liver, or kidney problems. You must also inform your doctor if you have diabetes, low blood pressure or are severely dehydrated due to excessive vomiting or diarrhea.

TIGATEL H 40MG TABLET is also not suitable for use in pregnant or breastfeeding women as it may cause serious harm to the growing baby. Stop taking TIGATEL H 40MG TABLET and inform your doctor immediately if you become pregnant while undergoing therapy with TIGATEL H 40MG TABLET.

The most common side effects of taking TIGATEL H 40MG TABLET are low blood pressure, dizziness, low or high blood potassium levels, pins and needles, muscle pain, diarrhoea, dry mouth, erectile dysfunction and increased blood uric acid levels. Contact your doctor if any of these side effect worsens.

USES OF TIGATEL H 40MG TABLET

• Management of Hypertension (high blood pressure)

HOW TIGATEL H 40MG TABLET WORKS

TIGATEL H 40MG TABLET is an antihypertensive medicine. It relaxes your blood vessels and improves blood flow across them. It also reduces thickness of the blood by removing excess fluids from the body in the form of urine. Collectively, these actions reduce the strain on the heart and helps the heart to pump blood more smoothly with less pressure.

DIRECTIONS FOR USE

• Take TIGATEL H 40MG TABLET as directed by your physician
• Swallow the medicine with a glass of water. Do not crush or chew the medicine.
• Try to take TIGATEL H 40MG TABLET at the same time each day.
• TIGATEL H 40MG TABLET can be taken with or without food.
• Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition.
• Continue to take TIGATEL H 40MG TABLET for the stipulated duration instructed by your doctor without any interruption to achieve better results.

SIDE EFFECTS OF TIGATEL H 40MG TABLET

Common Side Effects of TIGATEL H 40MG TABLET:

• Dizziness
• Low or high blood potassium levels
• Pins and needles (paraesthesia)
• Vertigo (spinning sensation)
• Fast or irregular heartbeat
• Low blood pressure causing dizziness while standing up
• Diarrhoea, dry mouth, flatulence
• Back pain, muscle spasm or pain
• Erectile dysfunction (inability to get or keep an erection)
• Increased blood uric acid levels
• Sore throat, sinus inflammation, common cold, cough
• Urinary tract infections
• Anaemia
• Kidney problems

Stop taking TIGATEL H 40MG TABLET and contact your doctor immediately if you experience any of the following side effects such as:

• Eye pain, swelling, decrease in vision (signs of fluid accumulation in the eye)
• Skin reactions or unexpected skin lesions
• Increased skin sensitivity towards sunlight, sunburn, redness, itching, swelling and blistering of skin
• Signs of severe dehydration (such as dry mouth, feeling weak or tired, drowsiness, restlessness, muscle weakness, nausea, vomiting and fast heart rate)

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking TIGATEL H 40MG TABLET inform to your doctor, if you are taking any of these medicines:

• Antidepressants (such as lithium, citalopram, fluoxetine, paroxetine, nefazodone, St. John’s wort)
• Heart medicines (such as aliskiren, bosentan, methyldopa, guanethidine, captopril, enalapril, lisinopril, verapamil, diltiazem, losartan, valsartan)
• Anti-arrhythmic agents (Ex. quinidine, disopyramide, amiodarone, sotalol, digoxin)
• Potassium supplements or potassium-sparing diuretics such as spironolactone, triamterene or amiloride (used to retain or increase potassium levels in the body)
• Non-steroidal anti-inflammatory drugs (used for pain relief) such as indomethacin, celecoxib, ibuprofen, aspirin
• Heparin (a medicine used to manage or manage blood clots)
• Antibiotics (Ex. erythromycin, clarithromycin, telithromycin, trimethoprim, sparfloxacin, pentamidine, penicillin-G)
• Baclofen (a medicine used for relaxing muscles)
• Amifostine (a kidney protectant used along with chemotherapeutic agents)
• Antipsychotics (Ex. pimozide, amisulpride, haloperidol, thioridazine, chlorpromazine, levomepromazine)
• Corticosteroids (Ex. Prednisolone)
• Amphotericin B (a medicine used to manage fungal infections)
• Carbenoxolone (a medicine used to manage mouth ulcers)
• Allopurinol (a medicine used to manage gout)
• Anticancer agents (such as cyclophosphamide or methotrexate)
• Laxatives (used to manage constipation) Ex. lactulose
• Corticotropin (a medicine used to correct hormone problems)
• Antihyperlipidemic agents (such as cholestyramine and colestipol)
• Antidiabetic agents (such as Insulin, metformin)
• Noradrenaline (a medicine used to increase blood pressure)
• Tubocurarine, dantrolene (medicine used as a muscle relaxant)
• Calcium supplements and/or vitamin D supplements
• Atropine or biperiden used for abdominal or stomach spasms or cramps
• Amantadine (medicine used to manage Parkinson’s disease)
• Medicines used to manage allergic reactions (Ex. terfenadine)

Overdosage:

If you or anyone else accidentally take too much of TIGATEL H 40MG TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage may cause undesirable effects such as low blood pressure, rapid heartbeat, vomiting, slow heartbeat, dizziness, low blood levels of potassium (resulting in nausea, sleepiness and muscle cramps or irregular heartbeat), reduced kidney function including kidney failure.

SYNOPSIS