INTRODUCTION ABOUT TIGATEL CH 40/12.5MG TABLET

TIGATEL CH 40/12.5MG TABLET is used to manage hypertension (high blood pressure) in affected individuals when monotherapy with chlorthalidone or telmisartan becomes inadequate to control the condition. It is also used as initial therapy in patients who are indicated for multiple drug therapy to control high blood pressure. It is a combination of Chlorthalidone and Telmisartan which belongs to the group of medicines called Diuretics and Angiotensin II receptor blockers, respectively.

TIGATEL CH 40/12.5MG TABLET is not recommended for use in patients who are allergic to chlorthalidone, telmisartan, and/or any sulphonamide-derived medicines. It is also not recommended for use in patients suffering from anuria and severe liver impairment. Before taking the medicine, inform your doctor if you have liver problems, kidney problems and/or heart problems (such as congestive heart failure).

TIGATEL CH 40/12.5MG TABLET is not recommended for use during pregnancy and in women planning for pregnancy. It is also not recommended for use in breastfeeding women since it passes through breast milk. It should be used with caution in children and adolescents (aged 6 to 18 years) and in elders (aged 65 years and above). The most common side effects are back pain, sore throat, nausea, abdominal pain, indigestion, diarrhoea, and/or headache. Consult your doctor if any of these symptoms worsen.

USES OF TIGATEL CH 40/12.5MG TABLET

• Used to manage hypertension

HOW TIGATEL CH 40/12.5MG TABLET WORKS

TIGATEL CH 40/12.5MG TABLET helps to lower blood pressure, where telmisartan works by blocking angiotensin (a hormone responsible for regulating blood pressure and maintaining fluid balance in the body) which leads to relaxation of blood vessels and Chlorthalidone works by removing extra water and certain electrolytes from the body which leads to relaxation of blood pressure and improved blood flow thus reducing high blood pressure in affected individuals.

DIRECTIONS FOR USE

• Take TIGATEL CH 40/12.5MG TABLET as advised by your physician
• Swallow the medicine with a glass of water. Do not crush or chew the medicine
• Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition

SIDE EFFECTS OF TIGATEL CH 40/12.5MG TABLET

Common side effects of TIGATEL CH 40/12.5MG TABLET:

• back pain
• abdominal pain, indigestion
• diarrhoea
• headache, dizziness, feeling weak
• dry mouth

Stop taking TIGATEL CH 40/12.5MG TABLET and contact your doctor immediately if you experience any of the following side effects:

• Signs of hypokalaemia (low potassium level in blood) such as muscular weakness, racing heartbeat, extreme tiredness

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking TIGATEL CH 40/12.5MG TABLET, inform your doctor if you are taking any of the following medicine:

• Anti-hypertensive agents (Ex. aliskiren, ramipiril, guanethidine, methyldopa)
• Cardiac glycosides (Ex. Digoxin)
• Anti-maniac agents (Ex. Lithium)
• Selective COX-2 inhibitors (Ex. celecoxib, indometacin)
• Anti-diabetics (Ex. metformin, glibenclamide, insulin)
• Anti-cholinergic agents (Ex. atropine, biperiden)
• Calcium salts, Vitamin D
• Immunosuppressants (Ex. Cyclosporin)
• β-blockers (Ex. acebutolol, atenolol)
• Vasodilators (Ex. benazepril, lisinopril)
• calcium antagonists (Ex. amlodipine, diltiazem)
• ACE inhibitors (Ex. benazepril, captopril)
• Anti-lipidemic agents (Ex. Cholestyramine)
• Corticosteroids (Ex. prednisolone)
• Beta-2 agonists (Ex. salbutamol, terbutaline)
• Antifungals (Ex. Amphotericin)
• Triterpenoids (Ex. Carbenoxolone)
• Cardiac glycosides (Ex. Digitalis)
• Xanthine oxidase inhibitor (Ex. Allopurinol)
• Adamantanes (Ex. Amantadine)
• Benzothiadiazine (Ex. Diazoxide)
• Cytotoxic agents (Ex. cyclophosphamide, methotrexate)

B. Drug-Food interaction:

Avoid having very strict low-salt diet while taking TIGATEL CH 40/12.5MG TABLET since it may cause undesirable effects.

Overdosage:

If you or anyone else accidentally take too much of the medicine, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are low blood pressure, dizziness, fast heart rate, slow heart rate, nausea, sleeplessness, hypovolaemia (low blood volume), and electrolyte imbalances (associated with an irregular heartbeat and muscle spasms).

SYNOPSIS