INTRODUCTION ABOUT STAMLO 2.5MG TABLET

STAMLO 2.5MG TABLET is a medication used primarily for the management of high blood pressure (hypertension) and angina (Prinzmetal’s or variant angina). The active ingredient, Amlodipine , is a calcium channel blocker that helps relax blood vessels, reducing strain on the heart and lowering blood pressure and chest pain.

You can take STAMLO 2.5MG TABLET at any time of the day, with or without food. For the best results, try to take it around the same time every day. Always follow your doctor’s instructions and take the medication for as long as prescribed, even if you feel fine. Sudden discontinuation may worsen your condition, as high blood pressure often has no visible symptoms.

Complement your therapy with regular physical activity, a healthy diet, and weight management to maintain optimal blood pressure levels.

Before taking STAMLO 2.5MG TABLET, inform your doctor if you have any liver, heart, or kidney problems, as this may affect your dosage. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Always share details about any other medications you are taking, especially those for blood pressure or heart conditions, as interactions could affect the efficacy of STAMLO 2.5MG TABLET.

Regular monitoring of blood pressure is essential to ensure the medication is working as intended and to adjust the dosage if needed. The most common side effects of taking STAMLO 2.5MG TABLET are headache, edema (swelling), fatigue, nausea, abdominal pain, and drowsiness. If these symptoms persist or worsen, consult your doctor.

USES OF STAMLO 2.5MG TABLET

• high blood pressure (hypertension)
• Angina (prinzmetal’s or variant angina)

Benefits of STAMLO 2.5MG TABLET in Hypertension:

STAMLO 2.5MG TABLET works by relaxing and widening blood vessels, which helps to reduce blood pressure. It improves overall circulation, making it easier for the heart to pump blood, thus effectively managing high blood pressure and reducing the risk of heart disease and stroke.

Benefits of STAMLO 2.5MG TABLET in Angina:

By improving blood flow and reducing cholesterol plaque build-up in arteries, STAMLO 2.5MG TABLET helps reduce angina (heart-related chest pain) caused by blocked or narrowed coronary arteries. This reduces the frequency and intensity of chest pain episodes, allowing for improved quality of life for patients with heart disease.

Other Benefits:

By controlling blood pressure, STAMLO 2.5MG TABLET helps reduce the chances of heart attacks, strokes, and other serious cardiovascular events in patients suffering from hypertension and angina.

HOW STAMLO 2.5MG TABLET WORKS

STAMLO 2.5MG TABLET contains Amlodipine. In patients with high blood pressure it works by relaxing blood vessels, so that blood passes through them more easily. In patients with angina it works by improving blood supply to the heart muscle which then receives more oxygen and as a result chest pain is managed. This medicine does not provide immediate relief of chest pain from angina.

DIRECTIONS FOR USE

• Take STAMLO 2.5MG TABLET exactly as prescribed by your healthcare provider. It is usually taken once a day, with or without food. For best results, try to take it at the same time each day.
• Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Recommended Dosage:

• The typical starting dose of Amlodipine is 5mg per day. Depending on your condition and response to the medication, your doctor may adjust the dose.
• Always follow your doctor's instructions regarding the dose and duration of treatment for optimal results in managing cholesterol levels and cardiovascular health.

What to Do if You Miss a Dose?

• If you miss a dose of STAMLO 2.5MG TABLET, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose. Do not double the dose to make up for the missed one, as this may lead to side effects or complications.

Overdosage

• Symptoms of Overdosage: Overdosing on STAMLO 2.5MG TABLET may cause symptoms such as dizziness, confusion, muscle pain, or weakness. If you suspect an overdose, seek immediate medical attention or contact your healthcare provider.

SIDE EFFECTS OF STAMLO 2.5MG TABLET

Like all medicines, STAMLO 2.5MG TABLET may cause certain side effects although not everybody gets them

Common Side Effects of STAMLO 2.5MG TABLET:

• Swelling of ankles
• headache, dizziness
• sleepiness, tiredness, muscle cramps
• palpitations (awareness of heart beat)
• flushing
• abdominal pain, diarrhoea, constipation, indigestion
• nausea
• altered bowel habits
• visual disturbances, double vision
• vomiting
• joint or muscle pain, back pain

When to consult your doctor?

Stop taking the medicine, and contact your doctor immediately if you experience any of the following side effects:

• sudden wheeziness, chest pain, shortness of breath or difficulty in breathing
• swelling of the tongue and throat which causes great difficulty breathing
• severe skin reactions including an intense skin rash, hives, reddening of the skin over your whole body, severe itching, blistering, peeling and swelling of the skin, inflammation of mucous membranes (stevens-johnson syndrome, toxic epidermal necrolysis) or other allergic reactions

HOW TO MANAGE SIDE EFFECTS

Edema (Swelling of Ankles):

To manage ankle swelling caused by STAMLO 2.5MG TABLET, you can try the following home remedies:

• Elevate Your Legs: Elevating your feet above heart level for 15-20 minutes a few times a day can help reduce swelling by encouraging fluid to flow back into your body.
• Limit Salt Intake: Reducing salt (sodium) in your diet can prevent fluid retention, which may help control swelling. Avoid processed and salty foods.
• Exercise Regularly: Gentle exercises like walking or leg movements (e.g., ankle circles) can help stimulate blood flow and reduce swelling.
• Stay Hydrated: Drinking plenty of water helps flush excess salt and fluids from your body, which may reduce swelling.
• Avoid Prolonged Sitting or Standing: If you are sitting or standing for long periods, take breaks to move around and stretch your legs to improve circulation.

If the swelling persists or causes discomfort, consult your doctor. They may adjust your amlodipine dosage or explore other treatments to alleviate the side effect.

WARNING & PRECAUTIONS

SAFETY ADVICE

Expert Advice to maximise the effects of STAMLO 2.5MG TABLET:

To get the best results from STAMLO 2.5MG TABLET, here are some expert tips for effective management of hypertension and angina:

• Take Consistently at the Same Time: For optimal results, take STAMLO 2.5MG TABLET at the same time every day to maintain a steady level of the medication in your body.
• Follow a Healthy Diet: Incorporate a heart-healthy diet, rich in fruits, vegetables, and whole grains, while limiting salt and processed foods to help lower blood pressure and support cardiovascular health.
• Stay Active: Regular physical activity, such as walking or light exercise, can enhance the effectiveness of STAMLO 2.5MG TABLET by improving circulation and helping to maintain a healthy weight.
• Monitor Your Blood Pressure: Regularly check your blood pressure to ensure that the medication is effectively controlling it. This also helps to adjust the dosage if needed.
• Avoid Alcohol and Smoking: Limit alcohol consumption and quit smoking to prevent interference with the medication's effects and improve overall heart health.
• Follow Doctor’s Instructions: Always adhere to your doctor’s advice regarding dosage, lifestyle changes, and follow-up appointments to ensure maximum benefit from STAMLO 2.5MG TABLET.

INTERACTIONS

A. Drug-Drug Interactions:

1. CYP3A4 Inhibitors (e.g., Ketoconazole, Itraconazole, Ritonavir)

Effect: These medications can increase the blood levels of Amlodipine, leading to a higher risk of side effects like severe low blood pressure (hypotension), dizziness, or swelling in the ankles and feet.

2. Nitrates (e.g., Nitroglycerin, Isosorbide Dinitrate)

Effect: Combining Amlodipine with nitrates can result in severe hypotension (low blood pressure), causing dizziness, fainting, or even shock, especially when used in patients with heart disease.

3. Alpha-blockers (e.g., Doxazosin, Prazosin)

Effect: When used together, Amlodipine can intensify the blood pressure-lowering effects of alpha-blockers, leading to excessive hypotension and an increased risk of dizziness or fainting, particularly when standing up.

Other drug-drug interactions are:

• Antibiotics (Ex. rifampicin, erythromycin, clarithromycin)
• St. John’s Wort (Ex. hypericum perforatum)
• Heart medicines (Ex. verapamil, diltiazem)
• Skeletal muscle relaxant (Ex. Dantrolene)
• Immunosuppressants (Ex. tacrolimus, sirolimus, temsirolimus, everolimus, ciclosporin)
• HMG-CoA reductase inhibitors (Ex. Simvastatin)

B. Drug-Food interactions:

Grapefruit juice and grapefruit is not recommended while taking the medicine. This is because grapefruit and grapefruit juice can lead to an increase in the blood levels of the active ingredient amlodipine, which can cause an unpredictable increase in the blood pressure lowering effect of the medicine.

SYNOPSIS

MORE INFORMATION

When taking STAMLO 2.5MG TABLET for managing high blood pressure (hypertension) or angina (chest pain), combining it with healthy lifestyle choices and a balanced diet can significantly enhance the medication's effectiveness. Here are some expert tips:

1. Follow a Heart-Healthy Diet:

• Limit Salt Intake: Reduce your sodium intake to help manage blood pressure. Aim for less than 2,300 mg of sodium per day, or lower if advised by your doctor.
• Increase Fruits and Vegetables: Include plenty of potassium-rich foods like bananas, oranges, leafy greens, and sweet potatoes to help regulate blood pressure.
• Opt for Whole Grains: Choose whole grains like oats, brown rice, and whole wheat bread instead of refined grains to improve heart health and control cholesterol levels.
• Healthy Fats: Focus on unsaturated fats (found in olive oil, nuts, and avocados) and avoid trans fats and excessive saturated fats that can increase cholesterol.

2. Maintain a Healthy Weight:

• Exercise Regularly: Aim for at least 30 minutes of moderate exercise (like walking or cycling) most days of the week. Regular physical activity helps reduce blood pressure, improve heart function, and maintain a healthy weight.
• Weight Management: If you are overweight, losing even a small amount of weight can significantly help in lowering blood pressure and improving heart health.

3. Limit Alcohol and Quit Smoking

• Limit Alcohol Consumption: Drinking alcohol in excess can increase blood pressure and reduce the effectiveness of medications like STAMLO 2.5MG TABLET. Stick to the recommended limits: up to one drink per day for women and two drinks per day for men.
• Quit Smoking: Smoking can increase the risk of heart disease and complications associated with hypertension. Quitting smoking improves overall heart health and reduces blood pressure.

4. Monitor Your Blood Pressure Regularly

• Keep track of your blood pressure readings at home to ensure that your STAMLO 2.5MG TABLET dosage is working effectively. Regular monitoring can help adjust treatment if needed.

5. Manage Stress

• Chronic stress can contribute to high blood pressure and heart-related issues. Incorporate stress-reducing techniques like yoga, meditation, or deep breathing exercises into your daily routine to help manage blood pressure.

6. Stay Hydrated

• Drink Plenty of Water: Staying hydrated helps regulate blood pressure and supports overall cardiovascular health.