INTRODUCTION ABOUT SGLTD M 10/500 TABLET

SGLTD M 10/500 TABLET is used to manage type-2 diabetes mellitus along with diet and exercise when diabetes cannot be controlled with other medicines. It is also used in combination with insulin or GLP-1 receptor agonist like liraglutide. It is a combination of Dapagliflozin and Metformin which belongs to the group of medicines called Antidiabetics. SGLTD M 10/500 TABLET helps to lowers blood glucose levels, where Dapagliflozin works by removing excess sugar from the body in the form of urine and Metformin works by inhibiting glucose production in the liver.

Prior to the management, your doctor may want you to take several blood tests to understand your existing kidney condition. Avoid consumption of alcohol while taking SGLTD M 10/500 TABLET as it may increase the risk of lactic acidosis. SGLTD M 10/500 TABLET is not recommended for use in patients with liver disease, moderate to severe kidney disease, recent heart attack or acute myocardial infarction, heart failure, septicemia or severe infection, diabetic ketoacidosis, hypoxemia or uncontrolled diabetes. Contact your doctor before taking the medicine.

SGLTD M 10/500 TABLET is not recommended for use in second and third trimester of pregnancy unless considered clearly necessary. SGLTD M 10/500 TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. SGLTD M 10/500 TABLET is not recommended for use in children and adolescents under 18 years of age. SGLTD M 10/500 TABLET should be used with caution in elderly patients (aged 65 years or above). The most common side effects of this medicine are diarrhea, stomach pain and loss of appetite. Contact your physician if any of the above side effects worsen or persists for a longer duration.

USES OF SGLTD M 10/500 TABLET

• Used in the management of type-2 diabetes mellitus

HOW SGLTD M 10/500 TABLET WORKS

SGLTD M 10/500 TABLET helps to lowers blood glucose levels, where Dapagliflozin works by removing excess sugar from the body in the form of urine and Metformin works by inhibiting glucose production in the liver.

DIRECTIONS FOR USE

• Take this medicine as advised by your physician
• Swallow this medicine as whole with a glass of water and do not crush or chew the medicine
• Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition

SIDE EFFECTS OF SGLTD M 10/500 TABLET

Common side effects of SGLTD M 10/500 TABLET:

• diarrhoea
• stomach pain
• loss of appetite
• genital infection (irritation, itching, unusual discharge, or odour)
• back pain
• increased urination
• decrease in creatinine clearance
• changes in taste
• constipation

Stop taking SGLTD M 10/500 TABLET and contact your physician immediately if you experience any of the following side effects:

• nausea, vomiting, stomach pain, muscle cramps, feeling of not being well with severe tiredness, body pain, increasing somnolence, difficulty in breathing, dizziness, light headedness, reduced body temperature, heartbeat, and low blood pressure (symptoms of lactic acidosis)
• dehydration, nausea, vomiting, abdominal pain, excessive thirst, generalised weakness, rapid weight loss, fast and deep breathing, confusion, unusual sleepiness or tiredness, fruity smell breath, a sweet or metallic taste in mouth, different odour to your urine or sweat (signs and symptoms of diabetic ketoacidosis)
• fever, chills, burning sensation while passing urine, back pain, or blood in urine (signs of urinary tract infection)
• weakness, shaking, sweating, drowsiness, dizziness, feeling very anxious, fast heartbeat, hunger, headache, change in vision, change in mood or confusion, and irritability (signs of low blood sugar)

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking SGLTD M 10/500 TABLET inform your doctor if you are taking any of the following medicine:

• Antidiabetics (Ex. glyburide, metformin, pioglitazone, sitagliptin, glimepiride, voglibose and insulin)
• Diuretics (Ex. furosemide, nifedipine, propranolol, enalapril, hydrochlorothiazide, bumetanide, valsartan, digoxin, ranolazine)
• Anticoagulants (Ex. warfarin)
• Antilipidemic agents (Ex. simvastatin)
• Anti-TB agents (Ex. isoniazid, rifampin)
• NSAID’s (Ex. ibuprofen, mefenamic acid)
• H2 blockers (Ex. cimetidine)
• Anticonvulsants (Ex. phenytoin or phenobarbital)
• Anti-viral agents (Ex. ritonavir, dolutegravir)
• Short-acting beta-2 adrenergic agonist (Ex. salbutamol)
• kinase inhibitors (Ex. vandetanib)
• carbonic anhydrase inhibitors (Ex. acetazolamide, zonisamide, or dichlorphenamide)
• Corticosteroids (Ex. betamethasone, dexamethasone)
• Ant-psychotics (Ex. fluphenazine)
• Hormones (Ex. levothyroxine)
• Oral contraceptives (Ex. levonorgestrel)  
• Vitamin supplements (Ex. nicotinic acid)

Overdosage:

If you or anyone else accidentally took too much of this medicine, consult your doctor immediately. Symptoms of overdose are hypoglycaemia and lactic acidosis.

SYNOPSIS