INTRODUCTION

PROTHIADEN 25MG contains Dosulepin which belongs to the group of medicines called Antidepressants. It is used in the management of depression (mood disorder causing persistent feeling of sadness and loss of interest) and also helps to reduce the feelings of anxiety (intense, excessive, persistent worry and fear about everyday situations), this medicine is used only when other medicines are not suitable.  

PROTHIADEN 25MG is not recommended for use in patients with liver problems, irregular heartbeat or any other heart problems, mania (feeling over excited with unusual behaviour), glaucoma (increased pressure in eye), prostate problems and fits.

Before taking PROTHIADEN 25MG inform your doctor if you have any planned surgeries (such as dental or general surgery), intolerance to certain sugars and thyroid problems. Avoid consumption of alcohol during management with PROTHIADEN 25MG as it can make the drowsiness worse.    

PROTHIADEN 25MG should be used in pregnant and breast-feeding women only if clearly advised by the doctor. It is not recommended for use in children and adolescents (below the age of 18 years) and it should be used with caution in elderly patients due to increased risk of certain side effects.  

The most common side effects of taking PROTHIADEN 25MG are dry mouth, blurred vision, dizziness, constipation, sedation and difficulty in passing urine. Consult with your doctor if any of the side effect worsens.

USES OF PROTHIADEN 25MG

• Manages depression
• Reduce the feelings of anxiety

HOW PROTHIADEN 25MG WORKS

PROTHIADEN 25MG acts on central nervous system (CNS) which works by enhancing the activity of certain neurotransmitters (such as serotonin and noradrenaline) in the brain. It also works by stopping the reabsorption of neurotransmitters into the nerve cells in the brain. Thus, results in prolonging their effects and helps to relieve depression and lighten the mood.

DIRECTIONS FOR USE

Take PROTHIADEN 25MG as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF PROTHIADEN 25MG

HOW TO MANAGE SIDE EFFECTS

Constipation:

Try to eat more high-fiber foods such as fresh fruit, vegetables, cereals, and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor for receiving alternate management for constipation.

Dry mouth:

Sip water regularly and other sugar free liquids. Do not use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. Consult your doctor if the symptom does not improve.

Dizziness:

Lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol, and drugs. Consult your doctor if the symptom gets worse.

Tiredness:

Drink plenty of fluid and eat balanced diet and frequent meals. Do regular minimal exercise and follow regular sleep schedule. Consult your doctor if the symptom gets worse.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug–Drug Interactions:

Before taking PROTHIADEN 25MG inform your doctor if you are taking any of the following medicines:

• medicines used to manage depression such as selective serotonin reuptake inhibitor (SSRIs) (Ex. citalopram, fluoxetine) and mono-amine oxidase inhibitor (MAOI) (Ex. isocarboxazid, phenelzine)   
• medicines used to manage underactive thyroid (Ex. Levothyroxine)
• medicines used to manage epilepsy (Ex. phenobarbitone), insomnia (Ex. amylobarbitone) and behavioural problems (Ex. methylphenidate)
• medicine containing an opioid (Ex. codeine, morphine, dihydrocodeine, co-proxamol and co-dydramol) (used to manage pain)
• medicines used to manage heart problems and asthma (also as cough and cold remedies), sympathomimetic agents (Ex. ephedrine, pseudoephedrine, adrenaline and noradrenaline)
• medicines used to manage high blood pressure (Ex. guanethidine) and regulate heartbeat (Ex. sotalol)
• terfenadine, astemizole (used to manage hay fever or allergy)
• halofantrine (used to manage malaria)

Overdosage:

If you or anyone else accidentally take too much of PROTHIADEN 25MG, consult your doctor immediately or visit the nearby hospital as it may seriously harm you and cause life-threatening problems. 

SYNOPSIS

MORE INFORMATION

• Keep PROTHIADEN 25MG out of reach of children
• Store at room temperature