INTRODUCTION ABOUT PREGEB M 75MG CAPSULE

PREGEB M 75MG CAPSULE is used for the management of neuropathic pain. It is a combination of Pregabalin and Methylcobalamin which belongs to the group of medicines called Anticonvulsants and Vitamin-B complex respectively. It consists of Methylcobalamin and Pregabalin where Methylcobalamin acts by rejuvenating the damaged neurons by improving the production of myelin and pregabalin acts by interfering with various pain signals travelling through the damaged nerves and the brain, thus leading to a significant pain relief in various neuropathic pain states.

Do not stop taking PREGEB M 75MG CAPSULE without consulting your doctor as it could precipitate withdrawal symptoms such as headache, insomnia, nausea, pain, diarrhea, flu syndrome, anxiety, nervousness, depression, convulsion, excessive sweating, dizziness and physical dependence. PREGEB M 75MG CAPSULE has high potential to cause addiction and therefore caution should be exercised among patients who already has a history of substance abuse.

PREGEB M 75MG CAPSULE is not recommended for use in pregnant or breastfeeding women unless advised by the doctor and in male patients who plan to father a child. The most common side effects are dizziness, sleepiness, headache, dry mouth, mood changes, fluid retention and weight gain. Consult your doctor if any of the side effects worsen.

USES OF PREGEB M 75MG CAPSULE

• Used to manage neuropathic pain

HOW PREGEB M 75MG CAPSULE WORKS

PREGEB M 75MG CAPSULE effectively alleviates the symptoms of various types of neuropathic pain, where Methylcobalamin acts by rejuvenating the damaged neurons by improving the production of myelin and Pregabalin acts by interfering with various pain signals travelling through the damaged nerves and the brain, thus leading to a significant pain relief in various neuropathic pain states.

DIRECTIONS FOR USE

• Take PREGEB M 75MG CAPSULE as advised by your physician
• Swallow PREGEB M 75MG CAPSULE with a glass of water. Do not crush or chew the medicine
• Your doctor will decide the correct dose and duration depending upon your age, body weight and disease condition

SIDE EFFECTS OF PREGEB M 75MG CAPSULE

Common side effects of PREGEB M 75MG CAPSULE:

• dizziness
• sleepiness
• headache
• common cold
• nausea, vomiting
• increased appetite
• constipation, diarrhea, flatulence, abdominal distension
• dry mouth
• feeling excited or pleasurable)
• impaired balance or coordination
• tremor (shaking)
• tingling and numbness in extremities)
• tiredness
• blurred vision
• spinning sensation
• muscle cramps
• pain in limbs, joints or back
• cervical spasm (a sudden, involuntary contraction of a muscle in the neck)
• joint swelling, muscle or neck pain

Stop taking PREGEB M 75MG CAPSULE and contact your doctor immediately if you experience any of the following side effects:

• severe allergic reactions (skin rash, itching, swelling of the face, lips, throat, neck and difficulty in breathing)
• symptoms of elevated creatine kinase (unexplained muscle pain, tenderness or weakness, accompanied by malaise or fever)

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking the medicine, inform your doctor if you are taking any of the following medicines:

• Anti-diabetics (Ex. metformin, pioglitazone, rosiglitazone)
• Anti-spasticity agents (Ex. dantrolene, baclofen)
• Opioid analgesics (Ex. morphine, pethidine)  
• CNS depressants (Ex. lorazepam)  
• Oral contraceptives (Ex. norethisterone and/or ethinyl estradiol)
• Antibiotics (Ex. Chloramphenicol)  
• Vitamins (Ex. folic acid, Vitamin C)
• Anti-lipidemic agents (Ex. cholestyramine or colestipol)
• Anti-gout agents (Ex. Colchicine)
• Antituberculosis agent (Ex. Para-amino salicylic acid)
• Electrolyte supplement (Ex. Potassium chloride)

Overdosage:

If you or anyone else accidentally takes too much of PREGEB M 75MG CAPSULE, contact your doctor immediately or go to a hospital straight away. Overdosage symptoms such as sleepiness, confusion, agitation, restlessness or seizures.

SYNOPSIS