Pioz MF 15mg Tablet 10'S
METFORMIN HYDROCHLORIDE 500MG+PIOGLITAZONE 15MG
₹ 127.00
₹142
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About this item
INTRODUCTION ABOUT PIOZ MF 15MG TABLET
PIOZ MF 15MG TABLET is a combination of Metformin and Pioglitazone, which belongs to the group of medicines called Antidiabetic agents. PIOZ MF 15MG TABLET is indicated as a second-line therapy for the management of type II diabetes mellitus in adult patients when diet, exercise, and therapy with other single agents do not result in adequate glycemic control.
Type II diabetes is a chronic medical condition in which the body does not make enough insulin, or the insulin produced does not work well. Symptoms include excessive urination, excessive thirst, hunger, fatigue, and blurred vision.
Along with management with PIOZ MF 15MG TABLET, follow a regular exercise and diet plan as advised by your doctor to achieve better results.
Before and during therapy with PIOZ MF 15MG TABLET, your doctor might recommend you take several blood tests to check your liver functions and monitor your body weight to rule out unwanted side effects.
Stop taking PIOZ MF 15MG TABLET and inform your doctor if you did not notice any improvements even after using this medicine for 3-6 months.
PIOZ MF 15MG TABLET is strictly not recommended for use in pregnant or breastfeeding women or in patients with active bladder cancer or hematuria (blood in urine). Consult your doctor before taking PIOZ MF 15MG TABLET.
PIOZ MF 15MG TABLET is not recommended for use in children and adolescents (aged under 18 years) due to a lack of safety data and an increased risk of serious side effects. It should be used with extreme caution in elderly patients due to the risk of bladder cancer, heart failure, or bone fracture.
The most common side effects of taking PIOZ MF 15MG TABLET are upper respiratory tract infections, headache, weight gain, changes in taste, nausea, vomiting, diarrhea, or stomach pain. Consult your doctor if any of the side effects worsen.
USES OF PIOZ MF 15MG TABLET
- To manage type II diabetes mellitus (as a second line of therapy)
HOW PIOZ MF 15MG TABLET WORKS
PIOZ MF 15MG TABLET helps to control blood sugar levels, where metformin works by reducing the amount of glucose released into the blood by the liver and pioglitazone acts by improving insulin sensitivity, thus leading to enhanced utilization of glucose in the peripheral organs and better glycemic control.
DIRECTIONS FOR USE
Take PIOZ MF 15MG TABLET as directed by your physician. Take this medicine with or without food, swallow the medicine as a whole and do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age and disease condition. Do not stop taking PIOZ MF 15MG TABLET without informing your doctor.
SIDE EFFECTS OF PIOZ MF 15MG TABLET
COMMON
- signs of upper respiratory tract infection (cough, sore throat, chest tightness, or wheezing)
- anemia
- hypoaesthesia (diminished sense of touch)
- headache
- visual disturbance
- arthralgia (joint pain)
- erectile dysfunction
- blood in urine (hematuria)
- weight gain
- nausea, vomiting, diarrhea, abdominal pain, and loss of appetite
- taste disturbance
- numbness
UNCOMMON
- difficulty sleeping
- inflammation of the sinus (sinusitis)
- bladder cancer
- flatulence
Stop taking PIOZ MF 15MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- serious allergic reaction (such as skin rash, itching, swelling of the face, lips, mouth, tongue, or throat, difficulty in swelling or breathing)
- symptoms of lactic acidosis (such as vomiting, stomach pain, decreased heartbeat, difficulty breathing, muscle cramps, general weakness with severe tiredness, or reduced body temperature)
- signs of liver inflammation (such as tiredness, loss of appetite, weight loss, with or without yellowing of the skin or whites of the eyes)
- signs of heart failure (such as unusual shortness of breath, a rapid increase in body weight, or localized swelling)
- signs of kidney problems (such as hematuria or bladder cancer)
- hypoglycemia (decreased blood glucose level)
- bone fracture
- blurred vision due to swelling at the back of the eye
HOW TO MANAGE SIDE EFFECTS
Diarrhea
Drink a lot of fluids, such as water or fruit juices, to keep yourself hydrated. Avoid taking any medicine on your own to manage diarrhea. Consult your doctor if the symptom does not improve.
Headache
Rest and relax. Drink plenty of fluids, such as water. Apply a pain-relieving balm to your forehead if required. Do not consume too much alcohol. Consult your doctor if the symptom does not improve.
Loss Of Appetite
Eat when you are hungry. Try to eat smaller meals more often than usual. Snack only when you're hungry. Try to eat a nutritious snack that is high in calories and protein, such as dried fruit and nuts. Consult your doctor if the symptom does not improve.
Nausea And Vomiting
Stick to simple meals. Avoid eating oily, fried, or spicy foods. Do not lie down or go to sleep immediately after eating. Consult your doctor if the symptom does not improve.
Stomach Pain
Rest and relax. Eat and drink slowly or try to have smaller and more frequent meals. Keep a heat pad on your stomach. Do not self-manage on your own and consult your doctor if the symptom does not improve on its own.
WARNING & PRECAUTIONS
PREGNANCY
ContraindicatedPIOZ MF 15MG TABLET is not recommended for use by pregnant women. Consult your doctor before taking PIOZ MF 15MG TABLET.
BREASTFEEDING
ContraindicatedPIOZ MF 15MG TABLET is not recommended for use during breastfeeding as it is not known whether it may be present in the breast milk. Consult your doctor before taking PIOZ MF 15MG TABLET.
DRIVING AND USING MACHINES
Use with CautionDo not drive or operate any machines if your ability is affected after taking PIOZ MF 15MG TABLET, and you should be alerted about the risk of low blood sugar levels before performing activities that require mental attention.
ALCOHOL
Consult your doctorAvoid consumption of alcohol while taking PIOZ MF 15MG TABLET due to the increased risk of lactic acidosis.
KIDNEY
ContraindicatedPIOZ MF 15MG TABLET is strictly not recommended for use in patients with kidney diseases (such as kidney failure, kidney dysfunction, hematuria (blood in urine), bladder cancer, or a history of bladder cancer). Consult your doctor before taking PIOZ MF 15MG TABLET.
LIVER
ContraindicatedPIOZ MF 15MG TABLET is not recommended for use in patients with active liver disease. Consult your doctor before taking PIOZ MF 15MG TABLET.
ALLERGY
ContraindicatedDo not take PIOZ MF 15MG TABLET if you are allergic to metformin or pioglitazone.
LUNGS
ContraindicatedPIOZ MF 15MG TABLET is not recommended for use in patients with infections affecting the lungs or bronchial system. Consult your doctor before taking PIOZ MF 15MG TABLET.
HEART DISEASE
ContraindicatedPIOZ MF 15MG TABLET is not recommended for use in patients with severe heart disease (such as grade III-IV heart failure, recent myocardial infarction, edema, or circulatory failure). Consult your doctor before taking PIOZ MF 15MG TABLET.
USE IN PEDIATRICS
ContraindicatedPIOZ MF 15MG TABLET is not recommended for use in children and adolescents (aged under 18 years) due to a lack of safety data and an increased risk of serious side effects. Consult your child’s doctor for advice.
USE IN GERIATRICS
Use with CautionPIOZ MF 15MG TABLET should be used with extreme caution in elderly patients (aged 65 years or older) due to the risk of bladder cancer, heart failure, and bone fracture. Proper dose adjustments and careful monitoring are required for such patients. Consult your doctor before taking PIOZ MF 15MG TABLET.
OTHERS
PIOZ MF 15MG TABLET is not recommended for use if you:
- have acute alcohol intoxication (abnormal behavior during or after alcohol consumption) or alcoholism
- have diabetic pre-coma
- have diabetic ketoacidosis (a diabetic complication causing nausea, vomiting, stomach pain, and rapid weight loss)
- have severe dehydration (either due to vomiting, diarrhea, or shock)
- have a severe infection
- are scheduled for an X-ray or scan using iodination contrast agents
- have an upcoming major surgery
Before taking PIOZ MF 15MG TABLET, inform your doctor if you:
- have or had a previous history of smoking
- had previous irradiation of the pelvic region
- are receiving chemotherapy or radiotherapy
- have macular oedema (swelling of the back of the eye with worsening of the vision)
- have polycystic ovary syndrome (the presence of cysts on your ovaries)
- are fasting or malnourished
INTERACTIONS
A. Drug-Drug interactions:
Before taking PIOZ MF 15MG TABLET, inform your doctor if you are taking any of these medicines:
- other medicines used to manage diabetes (Ex. insulin, glipizide, glyburide, and glimepiride)
- cyclophosphamide (a medicine used to manage certain types of cancer)
- non-steroidal anti-inflammatory drugs and COX-2-inhibitors (used to manage pain) Ex. celecoxib, etoricoxib, or ibuprofen
- gemfibrozil (a medicine used to manage blood cholesterol levels)
- rifampicin (a medicine used to manage tuberculosis)
- corticosteroids (used to manage inflammation) Ex. dexamethasone, prednisolone
- sympathomimetic agents (used to manage circulatory disorders) Ex. ephedrine, adrenaline, noradrenaline, isoprenaline, phenylephrine, and phenylpropanolamine
- diuretics (medicines used to increase urine output) Ex. furosemide, chlorothiazide, and hydrochlorothiazide
- angiotensin converting enzyme (ACE) inhibitors such as captopril, perindopril, and angiotensin II receptor antagonists such as azilsartan and losartan (used to manage low blood pressure)
- beta-2 agonists such as salbutamol or terbutaline (used to manage asthma)
- cimetidine (used to manage stomach ulcers)
- dolutegravir (used to manage HIV infection)
- ranolazine (used to manage chest pain)
- trimethoprim (used to manage bacterial infections)
- isavuconazole (used to manage fungal infections)
- crizotinib (used to manage non-small-cell lung cancer)
- olaparib (used to manage ovarian cancer)
Overdosage:
If you or anyone else accidentally takes too much of PIOZ MF 15MG TABLET, contact your doctor immediately or go to the nearest hospital right away, as it could lead to severe hypoglycemia or lactic acidosis. Symptoms of lactic acidosis might include nausea, vomiting, stomach pain with muscle cramps, decreased heartbeat, general weakness with severe tiredness, difficulty breathing, or reduced body temperature.
SYNOPSIS
| Drug | : | Metformin, Pioglitazone |
| Pharmacological Category | : | Biguanides, Thiazolidinediones |
| Therapeutic Indication | : | Type II diabetes mellitus |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep PIOZ MF 15MG TABLET out of reach of children
- Store at room temperature
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