INTRODUCTION ABOUT PANTOTAB 40 TABLET

PANTOTAB 40 TABLET is used to manage peptic ulcers, gastroesophageal reflux disease (GERD) and reflux esophagitis and its associated symptoms such as acidity, heartburn, acid reflux and pain in swallowing. It contains Pantoprazole which belongs to the group of medicines called Proton pump inhibitors. PANTOTAB 40 TABLET can also be used to manage peptic ulcer caused due to long-term use of non-steroidal anti-inflammatory drugs (such as aspirin, ibuprofen).

Take PANTOTAB 40 TABLET at least 1 hour before meals to achieve maximum benefits. During management with PANTOTAB 40 TABLET your doctor will closely monitor kidney functions, liver functions and blood magnesium levels to avoid the risk of unwanted side effects. Before taking inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have weak bones or any previous history of bleeding in the gut.

Consult your doctor before taking PANTOTAB 40 TABLET if you are pregnant or breastfeeding. The most common side effects are dryness of mouth, constipation and flatulence. You must also inform your doctor immediately if you experience severe tiredness with abnormal muscle movements, dizziness, confusion, disorientation and irregular heartbeat, as it could be a sign of low magnesium levels in blood.

USES OF PANTOTAB 40 TABLET

It is used to manage:

• Peptic ulcer and manages its recurrence
• Gastrointestinal Reflux disease (GERD)
• Reflux esophagitis (inflammation of the esophagus)
• Acidity, Heartburn, Pain in swallowing

HOW PANTOTAB 40 TABLET WORKS

PANTOTAB 40 TABLET contains Pantoprazole which helps to reduce gastric acid secretion by the blocking the actions of a protein membrane called H+K+Atpase (proton pump) across the stomach lining. As a result, it manages the worsening of ulcers, heals the existing ulcers and esophageal lesions and provides relief from the unpleasant symptoms of GI tract (such as acidity, heartburn and acid reflux).

DIRECTIONS FOR USE

• Take PANTOTAB 40 TABLET 30 minutes to 1 hour before meals or as advised by your physician
• Swallow the medicine with a glass of water. Do not crush or chew the medicine
• Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition
• Do not stop taking PANTOTAB 40 TABLET unless your doctor advice you to stop

SIDE EFFECTS OF PANTOTAB 40 TABLET

Common side effects of PANTOTAB 40 TABLET:

• benign polyps in the stomach
• headache
• dizziness, drowsiness
• feeling weak
• nausea or vomiting
• diarrhea, constipation, stomach pain, flatulence
• dry mouth

Stop taking PANTOTAB 40 TABLET and contact your doctor immediately if you experience any of the following side effects:

• severe allergic reactions (such as skin rash, itching, swelling of the lips, face or body and difficulty in breathing or swallowing)
• signs of liver problems (yellowing of the skin and eyes, dark urine and tiredness)
• severe skin reactions (such as redness, blistering, peeling of skin and bleeding in the lips, eyes, mouth, nose and genitals with fever)
• signs of kidney problem (such as lower back pain, painful urination)
• signs of low magnesium levels in blood (such as tiredness, abnormal muscle movements, dizziness, confusion, disorientation, irregular heartbeat)
• sudden weight loss, looking pale and weak (anemia)
• signs of bleeding in the gut (such as bloody vomits/stools)
• uncontrollable body movements (including eye and tongue), twisted neck and abnormal body posture

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking PANTOTAB 40 TABLET inform your doctor if you are taking any of the following medicines such as:

• Antifungal (Ex. ketoconazole, itraconazole and Posaconazole)
• Anti-cancer agents (Ex. erlotinib)
• Anticoagulants (Ex. warfarin and phenprocoumon)
• Antimetabolites (Ex. methotrexate)
• Anti-viral agents (Ex. atazanavir)
• Antidepressants (Ex. fluvoxamine)
• Antibiotics (Ex. rifampicin)
• Herbal medicine (Ex. St. John’s wort)

Overdosage:

If you or anyone else accidentally took more PANTOTAB 40 TABLET, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS