INTRODUCTION ABOUT PAN D CAPSULE

PAN-D Capsule is a combination medicine used to manage acid reflux, heartburn, burping, bloating indigestion, burning sensation in throat and food pipe and other signs of gastroesophageal reflux disease (GERD). It can also be used to heal inflammation of stomach lining (gastritis).

It contains a combination of Pantoprazole and Domperidone, which work together to reduce acid production and improve digestion.

Pan D Capsule is used to manage digestive health i.e peptic ulcers, gastroesophageal reflux disease (GERD) and reflux esophagitis. It is a combination of Domperidone and Pantoprazole which belongs to the group of medicines called Prokinetic Drugs and Proton pump inhibitors respectively. PAN D CAPSULE acts by reducing the production of gastric acid. It also speeds up the movement of food from the stomach to the intestines, thereby reducing the signs of nausea, vomiting and acid reflux. Due to these actions, it can also reduce the unpleasant signs of GI tract such as nausea, vomiting, indigestion, burping, bloating, acidity or heartburn.

It should be taken at least 15-30 minutes before meals. During management with PAN D CAPSULE your doctor will closely monitor your kidney functions, liver functions and blood magnesium levels to avoid the risk of unwanted side effects. Before taking PAN D CAPSULE inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have any blockage or tears in the gut or have weak bones.

PAN D CAPSULE is not recommended for use in patients bleeding from the gut. Consult your doctor before taking PAN D CAPSULE if you are pregnant or breastfeeding. The most common side effects are dryness of mouth, constipation and flatulence. Consult your doctor if any of these side effect bothers you. You must also inform your doctor immediately if you experience any signs of low magnesium levels in blood (such as tiredness, abnormal muscle movements, dizziness, confusion, disorientation, irregular heartbeat).

USES OF PAN D CAPSULE

• Relieves acidity, heartburn, indigestion, burping
• Inflammation or burning sensation in oesophagus due to acid reflux
• Management of stomach and intestinal ulcers
• Improves digestion by reducing nausea and vomiting

Benefits of PAN-D Capsule:

1. Relief from Acid Reflux and Heartburn:
   • PAN-D reduces excess acid production in the stomach, providing effective relief from acid reflux, heartburn, and symptoms of gastroesophageal reflux disease (GERD).
2. Management of Gastric Ulcers:
   • The pantoprazole component in PAN-D helps heal gastric and duodenal ulcers by reducing stomach acid, preventing further irritation, and promoting healing.
3. Management of Nausea and Vomiting:
   • Domperidone in PAN-D improves stomach motility, helping relieve nausea, vomiting, and bloating, especially in cases of indigestion or gastroparesis.
4. Improves Digestion and Reduces Bloating:
   • By improving the movement of food through the digestive tract, PAN-D helps alleviate bloating, gas, and discomfort caused by delayed stomach emptying.
5. Prevention of Acid-Related Damage:
   • Long-term use of PAN-D can reduce complications like esophagitis (inflammation of the esophagus) and protect the stomach lining from damage due to chronic acid production or use of NSAIDs.

Benefits of PAN-D in Pregnancy:

PAN-D Capsule can be helpful during pregnancy to relieve common issues like acid reflux, heartburn, nausea, and bloating, which occur due to hormonal changes and pressure on the stomach.

The combination of pantoprazole and domperidone works by reducing excess stomach acid and improving digestion, ensuring better comfort and nutrient absorption.

However, since the safety of domperidone during pregnancy is not fully established, PAN-D should only be used if prescribed by a doctor, who will weigh the benefits against potential risks. Always consult your doctor before using this medication during pregnancy.

HOW PAN D CAPSULE WORKS

PAN-D Capsule works by combining two key ingredients, pantoprazole and domperidone, to relieve digestive issues like acidity, heartburn, and nausea.

• Pantoprazole reduces the amount of acid produced in the stomach, helping to heal irritation and prevent discomfort caused by excess acid.
• Domperidone improves the movement of food through the stomach, which reduces bloating, nausea, and the feeling of fullness.

Together, these actions make PAN-D effective in treating conditions like acid reflux, indigestion, and stomach discomfort, providing quick and long-lasting relief. Always take it as directed by your doctor for the best results.

DIRECTIONS FOR USE

Take PAN-D Capsule as advised by your doctor. Strictly follow the dosing instructions recommended by your doctor for achieving best results.

How to Take PAN-D Capsule

• Swallow the capsule whole with a glass of water. Do not crush or chew it.
• Take the capsule 15-30 minutes before meals for optimal effectiveness.
• Follow your doctor’s instructions on the exact dosage and duration.

Dosage Instructions for PAN-D Capsule

• The usual dosage is once or twice a day, depending on the severity of your condition.
• Do not exceed the prescribed dose to avoid unwanted side effects.
• Always consult your doctor for any dosage adjustments.

PAN-D for Pregnancy

• Use PAN-D during pregnancy only if prescribed by your doctor after assessing risks and benefits.
• It may help manage acid reflux, heartburn, and nausea common in pregnancy.
• Avoid self-medicating and discuss all safety concerns with your doctor.

Best Time to Take PAN-D to Relieve Acid Reflux

• Take PAN-D in the morning, 15-30 minutes before breakfast, for best results.
• If prescribed twice a day, take the second dose before your evening meal.

Why PAN-D is Taken Before Food?

• Taking PAN-D before food allows pantoprazole to block acid production before meals stimulate acid secretion.
• This timing ensures maximum absorption and effectiveness in preventing heartburn and acid reflux.
• It also helps domperidone improve digestion efficiently.

What Happens if I Take PAN-D After Food?

• The effectiveness may reduce because pantoprazole is best absorbed on an empty stomach.
• Taking it after food may delay relief from acid reflux or heartburn.
• For best results, always follow your doctor’s timing instructions.

How Long Should PAN-D Be Taken For?

• Treatment duration depends on the condition being treated and is usually for 2-4 weeks or as advised by your doctor.
• Long-term use should be monitored regularly to avoid potential side effects like nutrient deficiencies.
• Never stop the medication abruptly without consulting your doctor.

What If I Missed a Dose of PAN-D?

• Take the missed dose as soon as you remember, unless it’s close to your next scheduled dose.
• Do not take two doses together to make up for the missed one.
• Stick to your regular schedule to ensure consistent relief.

Overdosage Instructions

• If you accidentally take more PAN-D than prescribed, seek immediate medical attention.
• Symptoms of overdose may include dizziness, severe nausea, or abdominal pain.
• Avoid taking extra doses to compensate for missed ones, as this increases the risk of side effects.

SIDE EFFECTS OF PAN D CAPSULE

Like all medicines, PAN-D Capsule may cause certain side effects in some individuals, although not everybody gets them.

Common side effects of PAN-D Capsule:

• Headache
• Dizziness
• Diarrhea
• Dry mouth
• Benign polyps in the stomach

PAN D – Safety During Pregnancy:

• PAN-D can be used during pregnancy if prescribed by a doctor, primarily to manage conditions like acid reflux, heartburn, or severe nausea.
• However, the safety of domperidone during pregnancy is not fully established, so it should only be used when the benefits outweigh the risks.
• Always consult your doctor before taking PAN-D during pregnancy to ensure it is safe for you and your baby.

PAN D – Long-Term Usage and Safety

• Long-term use of PAN-D may be safe under a doctor’s supervision, especially for chronic conditions like GERD or gastritis.
• Prolonged use could lead to side effects such as vitamin B12 deficiency, low magnesium levels, or bone weakness, so regular monitoring is essential.
• Do not continue PAN-D for longer than prescribed and consult your doctor periodically to assess its necessity.

When To Seek Medical Attention?

Stop taking PAN-D Capsule and consult your doctor immediately if you experience any of the following side effects:

• severe allergic reactions (such as skin rash, itching, swelling of the lips, face or body and difficulty in breathing or swallowing)
• signs of liver problems (yellowing of the skin and eyes, dark urine and tiredness)
• severe skin reactions (such as redness, blistering, peeling of skin and bleeding in the lips, eyes, mouth, nose and genitals with fever)
• signs of kidney problem (such as lower back pain, painful urination)
• signs of low magnesium levels in blood (such as tiredness, abnormal muscle movements, dizziness, confusion, disorientation, irregular heartbeat)
• severe, persistent diarrhea 
• Osteoporosis and Fractures: Prolonged use of PPIs like Pantoprazole may reduce calcium absorption, increasing the risk of osteoporosis and bone fractures, especially in elderly individuals

WARNING & PRECAUTIONS

SAFETY ADVICE

Expert Tips and Best Practices for Managing GERD with PAN-D Capsule:

1. Take PAN-D Before Meals: Always take the capsule 15-30 minutes before your first meal of the day for optimal acid control and symptom relief.
2. Stick to Your Doctor’s Prescription: Use the medication exactly as directed by your doctor. Avoid skipping doses or self-adjusting the dosage.
3. Adopt a GERD-Friendly Diet: Avoid trigger foods like spicy, oily, or acidic foods, and eat smaller, more frequent meals to prevent acid reflux.
4. Elevate Your Head While Sleeping: Use an extra pillow or incline your bed to keep stomach acid from flowing back into the esophagus during sleep.
5. Maintain a Healthy Lifestyle: Incorporate regular exercise, maintain a healthy weight, and avoid smoking or alcohol, as these can worsen GERD symptoms.

Drug - Drug interaction

How Does PAN-D Interact with Other Medications?

1. Antifungal Medications (e.g., Ketoconazole, Itraconazole):
   • These drugs require an acidic stomach environment for proper absorption, and PAN-D reduces stomach acid, making them less effective.
2. Blood Thinners (e.g., Warfarin):
   • PAN-D may alter the effectiveness of blood thinners, increasing the risk of bleeding. Regular monitoring is essential.
3. HIV Medications (e.g., Atazanavir, Nelfinavir):
   • PAN-D can reduce the absorption and effectiveness of these antiretroviral drugs.
4. Antibiotics (e.g., Clarithromycin):
   • When combined, there may be an increased risk of side effects like diarrhea or abdominal discomfort.
5. Antacids or Sucralfate:
   • Taking these with PAN-D may reduce its absorption. It's advised to space out doses by at least 1-2 hours.

Drug - Food interaction

Top Drug-Food Interactions for PAN-D Capsule:

1. Alcohol:
   • Alcohol can irritate the stomach lining and worsen acid reflux, counteracting the effects of PAN-D.
2. Caffeine-Rich Beverages (e.g., Coffee, Tea, Soda):
   • Caffeine stimulates acid production, which may reduce the effectiveness of PAN-D.
3. Spicy or Acidic Foods (e.g., Citrus Fruits, Tomatoes):
   • These foods can aggravate acid reflux and counteract the relief provided by PAN-D.
4. High-Fat Meals:

Fatty foods delay stomach emptying, increasing the risk of acid reflux and reducing PAN-D's efficiency.