INTRODUCTION ABOUT NURATOR TABLET

NURATOR TABLET is a combination of Methylcobalamin, Nortriptyline and Pregabalin which belongs to the group of medicines called Vitamins, Antidepressants and Anticonvulsants respectively. It is used to manage diabetic peripheral neuropathic pain with coexistent vitamin B12 deficiency.

Neuropathic pain is a form of pain where there is a damage or injury to the nerves that transfer information between the brain and spinal cord from the skin, muscles and other parts of the body.

Patients taking NURATOR TABLET may have thoughts of harming or killing themselves. If at any time you have these thoughts, immediately consult your physician. Avoid consumption of alcohol during management with NURATOR TABLET as it may cause dizziness.

Before taking NURATOR TABLET, inform your physician if you have liver or kidney problems, diabetes and angioedema. NURATOR TABLET is not recommended for use in pregnant women unless advised by the doctor and not recommended for breast-feeding women.

Elderly patients above 65 years of age always should consult the physician before taking it. The most common side effect of NURATOR TABLET are dry mouth, dizziness, sleepiness, blurred vision and weight gain. Consult your doctor if any of the side effects worsen over the time.    

USES OF NURATOR TABLET

• Manage diabetic peripheral neuropathic pain with coexistent vitamin B12 deficiency

HOW NURATOR TABLET WORKS

NURATOR TABLET is a combination of methylcobalamin, nortriptyline and pregabalin, where methylcobalamin is a form of vitamin B that helps in the production of myelin (a substance that protects nerve fibers) and regenerates damaged nerve cells. Nortriptyline is a tricyclic antidepressant that increases the chemical messenger levels (serotonin and noradrenaline) that stops the movement of pain signals in the brain. Pregabalin is an anticonvulsant (alpha 2 delta ligand) that decreases pain by altering the calcium channel activity of the nerve cells. Together, methylcobalamin, nortriptyline and pregabalin helps to relieve neuropathic pain (pain from damaged nerves).

DIRECTIONS FOR USE

Always take NURATOR TABLET as directed by your physician. Take this medicine with or without food, swallow the medicine as a whole and do not crush or chew the medicine. Your doctor will decide the correct dose and duration of NURATOR TABLET for you depending upon your age, body weight and disease condition. Do not stop taking NURATOR TABLET without informing your doctor.

SIDE EFFECTS OF NURATOR TABLET

HOW TO MANAGE SIDE EFFECTS

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking NURATOR TABLET inform your physician if you are taking any of the following medicines:

• medicines used as opioid analgesics such as oxycodone, tramadol (used to manage severe pain)
• medicine used to manage depression and anxiety (Ex. lorazepam, diazepam, MAO inhibitors like isocarboxazid)
• medicines used to manage gastroesophageal reflux (Ex. cimetidine, ranitidine)
• oral contraceptives such as desogestrel and ethinyl estradiol (used to manage pregnancy)
• medicines used for cancer chemotherapy (Ex. arsenic trioxide)
• medicines used to manage bacterial infections (Ex. chloramphenicol, azithromycin, clarithromycin and linezolid)
• reserpine (used to manage high blood pressure)
• anticholinergic drugs such as dicyclomine (used to manage the symptoms of irritable bowel syndrome)
• sympathomimetic drugs such as norepinephrine (used to raise blood pressure in emergency condition)

Overdosage:

If you or anyone else accidentally takes too much of NURATOR TABLET, consult your physician immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep NURATOR TABLET out of reach to children
• Store at room temperature