INTRODUCTION ABOUT NEBI H TABLET

NEBI H TABLET is a combination of Hydrochlorothiazide and Nebivolol which belongs to the group of medicines called Antihypertensive agents. It is used to manage hypertension (high blood pressure).

Hypertension (also known as high blood pressure) is a medical condition in which the force of the blood exerted against the walls of the artery remains very high and as a result it may lead to severe damage to the blood vessels supplying several vital organs, such as heart, kidney or brain. If left unmanageed, it may cause serious complications such as heart attack, heart failure, stroke or even blindness.

By lowering blood pressure, NEBI H TABLET can also reduce the risk of heart attack (myocardial infarction) or stroke. During management with NEBI H TABLET your doctor will constantly monitor your kidney functions, blood pressure, electrolyte levels and blood sugar levels to avoid the risk of unwanted side effects.

Before taking NEBI H TABLET inform your doctor if you have any liver, kidney or heart problems (such as angina). You must also inform your doctor if you have asthma, diabetes, thyroid problems, poor blood circulation, psoriasis or dehydration as a precaution.

NEBI H TABLET is not recommended for use in patients with severe heart problems (such as heart failure or heart block). Consult your doctor before taking this medicine if you are pregnant or breastfeeding.

The most common side effects of taking this medicine are headache, dizziness, tiredness, tingling sensation, diarrhoea, constipation, shortness of breath and swollen hands or feet. Consult your doctor if any of these side effect worsens.

USES OF NEBI H TABLET

• Manage Hypertension (high blood pressure)
• Prevents the risk of heart attack or stroke

HOW NEBI H TABLET WORKS

NEBI H TABLET is an antihypertensive medicine. It contains two medicines namely, nebivolol and hydrochlorothiazide. Nebivolol works by blocking the actions of certain chemical messengers (such as adrenaline) in the body that increases heart rate and blood pressure.

Hydrochlorothiazide works by reducing the thickness of the blood by removing excess fluids from the body in the form of urine. Collectively, these actions improve blood flow, reduce the strain on the heart and helps the heart to pump more blood with less pressure.

DIRECTIONS FOR USE

Take NEBI H TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Try to take NEBI H TABLET at the same time each day. NEBI H TABLET can be taken with or without food.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition.

Continue to take NEBI H TABLET for the stipulated duration instructed by your doctor without any interruption to achieve better results.

SIDE EFFECTS OF NEBI H TABLET

HOW TO MANAGE SIDE EFFECTS

Nausea and vomiting:

Take NEBI H TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

Headache:

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking NEBI H TABLET inform to your doctor, if you are taking any of the following medicines such as:

• medicines that can depress the brain such as barbiturates (Ex. phenobarbital)
• narcotic drugs (used for pain relief) such as morphine, fentanyl, pethidine
• medicines used to reduce blood cholesterol levels (such as cholestyramine, colestipol)
• corticosteroids (used to manage inflammation) Ex. prednisolone
• corticotropin (a medicine used to correct hormone problems)
• noradrenaline (a medicine used to increase blood pressure)
• tubocurarine, dantrolene (medicines used to relax muscles)
• medicines used for pain and inflammation (such as ibuprofen or indomethacin)
• calcium channel blockers (used to manage heart problems) such as verapamil, diltiazem, amlodipine, felodipine, lacidipine, nifedipine, nicardipine, nimodipine and nitrendipine
• other medicines used to manage high blood pressure (such as clonidine, guanfacine, moxonidine, methyldopa, rilmenidine, Aliskiren, captopril, enalapril, ramipril, losartan, valsartan)
• medicines used to manage uneven heartbeat (such as digoxin, quinidine, hydroquinidine, amiodarone, cibenzoline, ­ecainide, disopyramide, lidocaine, mexiletine and propafenone)
• medicines used to manage anxiety (such as phenobarbital, chlorpromazine)
• medicines used to manage depression (such as lithium, amitriptyline, trazodone, paroxetine, fl­uoxetine and thioridiazine)
• medicines used to manage asthma (such as salbutamol, salmeterol, budesonide)
• medications used to manage cough and cold (such as pseudoephedrine)
• medicines used to manage glaucoma (such as timolol, pindolol)
• medicines used to manage diabetes (such as insulin, metformin, gliclazide, glibenclamide)
• anaesthetics (used to cause numbness or loss of sensation) such as lidocaine, sevoflurane, halothane
• cimetidine (a medicine used to manage stomach ulcers)
• antacids (medicines used to neutralise stomach acid) such as aluminium hydroxide, magaldrate
• medicines used for pain and inflammation (such as aspirin, ibuprofen, diclofenac)
• baclofen (a medicine used for relaxing muscles)
• amifostine (a kidney protectant used along with chemotherapeutic agents)

Overdosage:

If you or anyone else accidentally took excessive amount of this medicine, consult your doctor immediately or visit the nearby hospital straight away. Symptoms of overdosage might include low blood pressure, fast or slow heart rate, dizziness, kidney problems and shortness of breath.

SYNOPSIS

MORE INFORMATION

• Keep NEBI H TABLET out of reach to children
• Store NEBI H TABLET at normal room temperature