INTRODUCTION ABOUT NEBI AM TABLET

NEBI AM TABLET is a combination of Amlodipine and Nebivolol which belongs to the group of medicines called Antihypertensive agents. It is used to manage hypertension (high blood pressure). It can also be used to manage angina and heart failure.

Take NEBI AM TABLET as advised by your physician. Avoid drinking grapefruit juice while taking NEBI AM TABLET, as it could further decrease your blood pressure.

Before taking NEBI AM TABLET inform your doctor if you have any liver, kidney or heart problems (such as angina). You must also inform your doctor if you have asthma, diabetes, thyroid problems, poor blood circulation or psoriasis as a precaution.

NEBI AM TABLET is not recommended for use in patients with severe heart problems (such as heart failure or heart block). Consult your doctor before taking this medicine if you are pregnant or breastfeeding.

The most common side effects of taking NEBI AM TABLET are swelling of ankles or other body parts, headache, dizziness, sleepiness, tiredness, racing heartbeat, indigestion, constipation, tingling sensation and muscle cramps. Contact your doctor if any of these side effects trouble you.

USES OF NEBI AM TABLET

• Manage hypertension (high blood pressure)
• Manage and manages angina and heart failure

HOW NEBI AM TABLET WORKS

NEBI AM TABLET is an antihypertensive medicine. It relaxes your blood vessels and improves blood flow across them. It also slows down the heart rate and reduces the force of contraction of heart muscles. As a result, it reduces the strain on the heart, improves blood flow across the blood vessels and makes the heart to pump blood more smoothly and efficiently with less pressure.

DIRECTIONS FOR USE

Take NEBI AM TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Try to take NEBI AM TABLET at the same time each day. NEBI AM TABLET can be taken with or without food.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition.

Continue to take NEBI AM TABLET for the stipulated duration instructed by your doctor without any interruption to achieve better results.

SIDE EFFECTS OF NEBI AM TABLET

HOW TO MANAGE SIDE EFFECTS

Nausea and vomiting:

Take NEBI AM TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

Headache:

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Constipation:

Eat plenty of fibre rich foods such as fresh fruits, vegetables and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug - Drug interactions:

Before taking NEBI AM TABLET, inform your doctor if you are taking any of the following medicines such as:

• calcium channel blockers (used to manage heart problems) such as verapamil, diltiazem, amlodipine, felodipine, lacidipine, nifedipine, nicardipine, nimodipine and nitrendipine
• other medicines used to manage high blood pressure (such as clonidine, guanfacine, moxonidine, methyldopa, rilmenidine, aliskiren, captopril, enalapril, ramipril, losartan, valsartan)
• medicines used to manage uneven heartbeat (such as digoxin, quinidine, hydroquinidine, amiodarone, cibenzoline, ­ecainide, disopyramide, lidocaine, mexiletine and propafenone)
• medicines used to manage anxiety (such as phenobarbital, chlorpromazine)
• medicines used to manage depression (such as lithium, amitriptyline, trazodone, paroxetine, fl­uoxetine and thioridiazine)
• medicines used to manage asthma (such as salbutamol, salmeterol, budesonide)
• medications used to manage cough and cold (such as pseudoephedrine)
• medicines used to manage glaucoma (such as timolol, pindolol)
• medicines used to manage diabetes (such as insulin, metformin, gliclazide, glibenclamide)
• anaesthetics (used to cause numbness or loss of sensation) such as lidocaine, sevoflurane, halothane
• cimetidine (a medicine used to manage stomach ulcers)
• antacids (medicines used to neutralise stomach acid) such as aluminium hydroxide, magaldrate
• medicines used for pain and inflammation (such as aspirin, ibuprofen, diclofenac)
• baclofen (a medicine used for relaxing muscles)
• amifostine (a kidney protectant used along with chemotherapeutic agents)
• ketoconazole, itraconazole (used to manage fungal infections)
• ritonavir, indinavir, nelfinavir (used in management of HIV infections)
• rifampicin, erythromycin, clarithromycin (used to manage bacterial infections)
• dantrolene (a medicine used to manage muscle spasms)
• medicines used to control elevated cholesterol levels (Ex. simvastatin)
• medicines used to manage graft rejection and to suppress immune functions (such as tacrolimus, sirolimus, temsirolimus, everlimus, cyclosporine)
• St. John’s wort (an herbal medicine used to manage depression)

B. Drug - Food interaction:

Avoid drinking grapefruit juice while taking NEBI AM TABLET, as it could abnormally decrease your blood pressure and make you feel drowsy or faint.

Overdosage:

If you or anyone else accidentally took more NEBI AM TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage might include dizziness, fainting, light-headedness, low blood pressure, fast or slow heart rate, weakness, shock, cool or clampy skin, shortness of breath and kidney problems.

SYNOPSIS

MORE INFORMATION

• Keep NEBI AM TABLET out of reach to children
• Store NEBI AM TABLET at normal room temperature