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Natrise 15mg Tablet 4'S
TOLVAPTAN 15MG
₹ 528.00
₹587
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About this item
INTRODUCTION ABOUT NATRISE 15MG TABLET
NATRISE 15MG TABLET contains Tolvaptan, which belongs to the group of medicines called Vasopressin antagonists. It is used to manage low serum sodium levels in adults who have a "syndrome of inappropriate antidiuretic hormone secretion" (SIADH), a condition in which the kidneys retain too much water.
The symptoms of SIADH may include nausea, vomiting, headache, confusion, weakness, and feeling sick; muscle weakness, irritability, mental confusion, and tremors (involuntary shaking or movements affecting hands, legs, face, head, or vocal cords).
NATRISE 15MG TABLET is not recommended for use in patients having problems with kidney function. NATRISE 15MG TABLET should be used with caution in patients with diabetes, heart disease, liver problems, and a kidney disease called autosomal dominant polycystic kidney disease (ADPKD).
If you are pregnant or breastfeeding, consult your doctor for advice before taking NATRISE 15MG TABLET. NATRISE 15MG TABLET should not be used in children or adolescents under the age of 18. The most common side effects of taking NATRISE 15MG TABLET are thirst, dehydration, nausea, headache, and diarrhea. Consult your doctor if the symptom worsens.
USES OF NATRISE 15MG TABLET
- Manage low serum sodium levels (hyponatremia) in adults who have “syndrome of inappropriate antidiuretic hormone secretion” (SIADH)
HOW NATRISE 15MG TABLET WORKS
NATRISE 15MG TABLET works by suppressing vasopressin (a hormone that helps manage the loss of water from the body by reducing urine output) leading to increased urine production and a raise in sodium concentration in blood.
DIRECTIONS FOR USE
Take NATRISE 15MG TABLET as advised by your physician. Swallow this medicine, do not crush, or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
SIDE EFFECTS OF NATRISE 15MG TABLET
COMMON
- thirst
- signs of high sodium level such as restlessness, extreme thirst, confusion, and lethargy)
- excessive drinking of water
- dehydration
- nausea
- signs of high potassium levels like shortness of breath, chest pain, nausea, or vomiting
- signs of high creatinine in the blood such as swelling or oedema, high blood pressure, muscle cramps and chest pain
- signs of high uric acid (severe pain in joints, joint stiffness, difficulty in moving affected joints)
- increase or decrease in blood sugar level
- decreased appetite
- fainting
- headache
- dizziness
- low blood pressure when standing up
- constipation
- diarrhoea
- dry mouth
- patchy bleeding in the skin
- itching
- frequent urination
- tiredness, general weakness
- fever
- general feeling of being unwell
- blood in the urine
- signs of raised levels of liver enzymes in the blood include stomach pain, dark urine, itching, jaundice
UNCOMMON
- altered taste sensation
- signs of kidney problems such as loss of appetite, decreased urinary output, fatigue
RARE
Stop taking NATRISE 15MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- difficulty in urination
- symptoms of allergic reaction included swelling of the face, lips or tongue, itching, generalised rash, or severe wheezing or breathlessness
- feel sick, loss of appetite, upper right abdominal discomfort, dark urine, yellowing of skin or eyes (jaundice)
HOW TO MANAGE SIDE EFFECTS
Diarrhoea:
Drink lots of fluids, such as water or fruit juice, to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. Consult your doctor if your symptoms do not improve.
Dizziness:
When you feel dizzy, lie down or sit down immediately. If you're experiencing a severe episode of vertigo, lie in a dark, quiet place with your eyes closed. Vehicle driving should be avoided if you experience frequent dizziness without warning. Consult your doctor if your symptoms do not improve.
Dry mouth:
A dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Drink water at regular intervals. Do not use mouthwashes that contain alcohol because they can be drying. Consult your doctor if your symptoms do not improve.
WARNING & PRECAUTIONS
PREGNANCY
NATRISE 15MG TABLET is not recommended for use in pregnant women or if you think you might become pregnant. Women should use appropriate contraceptive measures to avoid pregnancy while taking this medicine. Consult your doctor before taking NATRISE 15MG TABLET.
BREASTFEEDING
NATRISE 15MG TABLET is not recommended for use in breastfeeding women. Discuss with your doctor before taking NATRISE 15MG TABLET.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you feel dizzy, weak or feeling of fainting for a short period after taking NATRISE 15MG TABLET. Consult your doctor before taking NATRISE 15MG TABLET.
ALCOHOL
Avoid consumption of alcohol as it may increase the risk of side effects of NATRISE 15MG TABLET.
KIDNEY
NATRISE 15MG TABLET is not recommended for use if you have improper kidney function (no urine production). NATRISE 15MG TABLET should be taken with caution in patients suffering from a kidney disease called autosomal dominant polycystic kidney disease (ADPKD). Consult your doctor before taking NATRISE 15MG TABLET.
LIVER
NATRISE 15MG TABLET should be used with caution in patients having liver disease. Consult your doctor before taking NATRISE 15MG TABLET.
ALLERGY
NATRISE 15MG TABLET is not recommended for use if you are allergic to Tolvaptan or Benzazepine derivatives (Ex. benazepril, conivaptan, fenoldopam mesylate or mirtazapine).
HEART DISEASE
NATRISE 15MG TABLET should be used with caution in patients having congestive heart failure. Consult your doctor before taking NATRISE 15MG TABLET.
OTHERS
NATRISE 15MG TABLET is not recommended for use if you have:
- hypernatremia (a condition which increases the salt in blood)
- any condition which is associated with a very low blood volume
- feeling of not realising when you are thirsty
Before taking NATRISE 15MG TABLET, inform your doctor if you have:
- cannot drink enough water or in fluid restricted diet
- have difficulties in urination or have an enlarged prostate
- diabetes
Use in pediatrics:
NATRISE 15MG TABLET is not recommended for use in children and adolescents (under 18 years of age). Consult your doctor before taking NATRISE 15MG TABLET.
Use in geriatrics:
NATRISE 15MG TABLET is used with caution in patients above 65 years of age. Consult your doctor before taking NATRISE 15MG TABLET.
INTERACTIONS
A. Drug-Drug interactions:
Before taking NATRISE 15MG TABLET, inform your doctor if you are taking any of the following medicine:
- ketoconazole (a medicine used against fungal infections)
- macrolide antibiotics such as erythromycin, azithromycin, and clarithromycin (medicines used to manage bacterial infections)
- diltiazem (a medicine used in the management of high blood pressure and chest pain)
- medicines that increase the salt in your blood or which contain large amounts of salt (Ex. Sodium bicarbonate, sodium chloride, diuretics like furosemide, and bumetanide)
- barbiturates like phenobarbital, and pentobarbital (medicines used to manage epilepsy/seizures and some sleep disorders)
- rifampicin (a medicine used against tuberculosis)
- digoxin (medicine used in the management of irregular heartbeat and heart failure)
- desmopressin (a medicine used to increase blood clotting factors)
B. Drug–Food interactions:
Do not eat grapefruit or drink grapefruit juice while you are taking this medicine as it can increase the risk of side effects of this medicine. Consult your doctor before taking NATRISE 15MG TABLET.
Overdosage:
If you or anyone else accidentally take too much of NATRISE 15MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are a rise in serum sodium concentration, polyuria, thirst, and dehydration/hypovolemia (profuse and prolonged aquaresis).
SYNOPSIS
| Drug | : | Tolvaptan |
| Pharmacological Category | : | Vasopressin antagonists |
| Therapeutic Indication | : | Low serum sodium levels |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep NATRISE 15MG TABLET out of reach from children
- Store at room temperature
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