INTRODUCTION ABOUT MEFTAL FORTE TABLET

MEFTAL FORTE TABLET is a combination of Mefenamic acid and Paracetamol, which belongs to a group of medicines called Non-steroidal Anti-inflammatory Drugs (NSAIDs) and Analgesics and Antipyretics. It is used to manage fever. It is also used for the management of mild to moderate pain, such as headaches, toothaches, joint or muscle pains, and period pain.

MEFTAL FORTE TABLET is not recommended for use in patients with asthma or aspirin-sensitive asthma, kidney or liver disease, or heart failure. Contact your doctor before taking.

Pregnant women should generally avoid using MEFTAL FORTE TABLET. Contact your doctor before taking.

MEFTAL FORTE TABLET is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking it.

MEFTAL FORTE TABLET is not recommended for use in children. Contact your doctor before taking.

MEFTAL FORTE TABLET should be used with caution in elderly patients (aged 65 years or above). Contact your doctor before taking.

The most common side effects of this medicine are nausea, vomiting, abdominal pain, diarrhea, constipation, indigestion, flatulence, anorexia, dry mouth, heartburn, peptic ulcers, perforation or GI bleeding, and ulcerative stomatitis. Contact your doctor if any of the above side effects worsen.

USES OF MEFTAL FORTE TABLET

It is used to manage:

• fever
• mild to moderate pain (headache, toothache, joint or muscle pains, and period pains)

HOW MEFTAL FORTE TABLET WORKS

MEFTAL FORTE TABLET helps to relieve fever and pain, where paracetamol acts on the hypothalamus (heat regulating center) of the brain, resulting in peripheral vasodilation, sweating, and loss of body heat, and it also increases the pain threshold by inhibiting COX-1 and COX-2 enzymes, and mefenamic acid works by inhibiting COX-1 and COX-2 enzymes, which are involved in prostaglandin synthesis (responsible for pain and inflammation).

DIRECTIONS FOR USE

Take MEFTAL FORTE TABLET as advised by your physician. It can be taken with or without food.

For Tablet, Capsule: Swallow MEFTAL FORTE TABLET with a glass of water. Do not crush or chew the medicine.

For Dispersible Tablet: Disperse the medicine in the specified quantity of water as mentioned in the label. Consume the medicine immediately after reconstitution.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight, and disease condition.

SIDE EFFECTS OF MEFTAL FORTE TABLET

HOW TO MANAGE SIDE EFFECTS

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Inform your physician if you are taking,

• cholestyramine (medicines used to decrease high cholesterol levels)
• metoclopramide and domperidone (medicine used to manage nausea and vomiting)
• warfarin (medicine used for managing blood clots)
• phenytoin (medicine used to manage seizures)
• isoniazid (medicines used for tuberculosis)
• medicine used for high blood pressure (captopril and diuretics like chlorthiazide, chlorthalidone)
• ibuprofen, ketoprofen (medicine used to manage pain)
• lithium (medicine used to manage depression and mania)
• methotrexate (medicines used to manage cancer)
• antacids (medicines used for heartburn or indigestion)
• medicine used to manage bacterial infections (Ex. chloramphenicol, aminoglycosides like amikacin, tobramycin, gentamicin, and quinolone antibiotics like ciprofloxacin)
• digoxin (medicine used for heart failure)
• medicines used to manage diabetes mellitus (Ex. glimepiride, metformin)
• antiplatelet like aspirin (medicine used to manage platelet aggregation)
• cyclosporine (medicines acting on the immune system)
• corticosteroids (medicines used to manage inflammation)
• mifepristone (medicines used to terminate pregnancy)
• tacrolimus (medicines used to manage atopic dermatitis)
• zidovudine (medicines used for HIV infection)

Overdosage:

If you or anyone else accidentally took too much of this medicine, consult your doctor immediately. Symptoms of overdose are pallor, nausea, vomiting, anorexia, abdominal pain or epigastric pain, lethargy, drowsiness, liver damage, abnormalities of glucose metabolism, and metabolic acidosis may occur.

SYNOPSIS

MORE INFORMATION