INTRODUCTION ABOUT MEDROL 16MG TABLET

MEDROL 16MG TABLET is used to manage various adrenal gland problems, including adrenal insufficiency, congenital adrenal hyperplasia, and nonsuppurative thyroiditis. It is also effective in managing autoimmune and inflammatory conditions affecting different parts of the body, such as rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus, psoriasis, optic neuritis, uveitis, asthma, and certain blood disorders like leukemia. Additionally, it helps manage inflammatory bowel diseases like Crohn's disease and ulcerative colitis, as well as tuberculous meningitis in the brain.

This medication is also prescribed for managing severe allergic reactions, including drug-induced hypersensitivity, atopic dermatitis, allergic conjunctivitis, and allergic rhinitis. It can prevent graft rejection after organ transplantation and support kidney health by reducing protein loss in the urine or increasing urine output in conditions like nephrotic syndrome.

It contains a medicine called Methylprednisolone which belongs to the group of medicines called Corticosteroids.

Take MEDROL 16MG TABLET as advised by your physician. Do not stop taking MEDROL 16MG TABLET or reduce the dose of methylprednisolone without consulting your doctor as it may lead to unpleasant withdrawal symptoms, especially if you are taking higher dose of methylprednisolone.

Before taking MEDROL 16MG TABLET inform your doctor if you any viral infections, or any liver, kidney or heart problems. You must also inform your doctor if you have hypertension, diabetes, thyroid deficiency, glaucoma, skin problem, gut inflammation, muscle problems, osteoporosis, any types of tumors or cancer in the body, depression or any other forms of mental illness.

It should be used in pregnant or breastfeeding women only if it is considered necessary by the physician. Avoid drinking grapefruit juice or eating grapefruit while taking MEDROL 16MG TABLET as it may lead to unwanted side effects.

The most common side effects of taking MEDROL 16MG TABLET are high blood pressure, swelling of body parts, muscle cramps or weakness, skin thinning, feeling sad or depressed and slowed growth in children. Consult your doctor if any of these side effect worsens.

You must also inform your doctor if you experience severe depression with suicidal thoughts or severe stomach pain with blood-stained stools or vomit.

USES OF MEDROL 16MG TABLET

It is used to manage the following disease conditions:

• adrenal insufficiency and its associated conditions
• bone and joint problems (Ex. rheumatoid arthritis, ankylosing spondylitis)
• skin and collagen disorders (Ex. systemic lupus erythematosus, psoriasis)
• eye problems (Ex. optic neuritis, uveitis or iritis)
• respiratory tract diseases (Ex. asthma, tuberculosis)
• blood cancer (leukemia), lymph cancer (lymphoma)
• problems of bowel and gut (Ex. Crohn’s disease and ulcerative colitis)
• brain problems (Ex. tuberculous meningitis)
• drug induced hypersensitivity reactions
• allergic reactions (such as atopic dermatitis, allergic conjunctivitis and allergic rhinitis)

It can also:

• reduce the risk of graft rejection following organ transplantation
• improve urine output or reduces protein loss in urine among patients having nephrotic syndrome

HOW MEDROL 16MG TABLET WORKS

MEDROL 16MG TABLET is a corticosteroid medicine with anti-inflammatory and immune suppressant properties. It boosts your body with sufficient corticosteroid levels (cortisol, aldosterone) during deficient conditions and helps your body to function properly.

It also reduces the release of certain chemicals (prostaglandins) in the body that causes inflammation. It manages graft rejection by suppressing the immune functions and protects your kidney from damage in patients with kidney problems.

DIRECTIONS FOR USE

• Take MEDROL 16MG TABLET as advised by your physician.
• Swallow the medicine with a glass of water.
• Do not crush or chew the medicine.
• Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
• Do not stop taking MEDROL 16MG TABLET without consulting your doctor.

SIDE EFFECTS OF MEDROL 16MG TABLET

Like all medications, this medicine may cause side effects, although they do not occur in everyone.

Common Side Effects of MEDROL 16MG TABLET:

• high blood pressure (causing headache, or a general feeling of being unwell)
• swelling of body parts
• muscle cramps, weakness or wasting
• cataract, blurred vision
• slowed growth in children
• moon shaped face (Cushingoid facies)
• feeling sad, mood changes, mania, anxiety
• problems in sleeping
• difficulty in thinking, confusion, loss of memory, hallucinations
• fear or frightening thoughts
• acne, poor wound healing
• skin thinning

Contact your doctor immediately if you experience any of the following side effects while undergoing therapy with MEDROL 16MG TABLET:

• signs of allergic reaction (such as skin rash, itching, blistering and peeling of the skin, swelling of the face, lips, mouth, throat which may lead to breathing difficulties)
• signs of bleeding in the gut (such as stomach pain which radiates until your back, bleeding from the anus, black or blood-stained stools, blood in vomit)
• increased infections causing fever or a general feeling of being unwell
• signs of flare up of a previous tuberculosis infection (such as coughing blood or pain in the chest)
• signs of pancreatitis (inflammation of pancreas causing severe stomach pain and vomiting)
• signs of blood clot in lungs (such as sharp chest pain, shortness of breath, coughing up blood)
• signs of increased pressure within the skull (such as severe headaches with vomiting, lack of energy and drowsiness) usually occurs once therapy is stopped
• thrombophlebitis (blood clots in vein supplying the legs causing leg pain, swelling, redness and tenderness)
• feeling depressed, suicidal thoughts
• blurred vision or other visual disturbances

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug - Drug interactions:

Before taking MEDROL 16MG TABLET, inform your doctor if you are taking any of the following medicines such as:

• acetazolamide (a medicine used to manage glaucoma or edema)
• aminoglutethimide or cyclophosphamide (used for managing cancer)
• anticoagulants (used for blood thinning) such as acenocoumarol, phenindione and warfarin
• anti-cholinergic medicines used to manage myasthenia gravis (such as distigmine and neostigmine)
• antibacterials (Ex. isoniazid, erythromycin, clarithromycin and troleandomycin)
• anti diabetics (Ex. metformin, glipizide)
• aprepitant or fosaprepitant (antiemitics)
• non-steroidal anti-inflammatory medicines (used for fever and pain relief) such as aspirin, ibuprofen
• antiepileptics (such as carbamazepine, phenytoin and primidone)
• carbenoxolone and cimetidine (antiulcer agents)
• ciclosporin, tacrolimus (immunosuppressants)
• Cardiovascular agents (such as digoxin, diltiazem or mibefradil)
• oral contraceptives (birth control pills) Ex. ethinylestridiol and norethisterone
• medicines used to manage HIV infection (such as ritonavir, indinavir, cobicistat)
• Antifungals (such as ketoconazole, amphotericin B, itraconazole)
• muscle relaxants (Ex. pancuronium or vecuronium)
• diuretics (used to manage edema and hypertension) Ex. furosemide, chlorothiazide, hydrochlorothiazide
• medicines used to manage asthma (such as aminophylline, salmeterol, formoterol)
• rifampicin and rifabutin (Antituberculosis)
• live vaccines

B. Drug - Food interaction:

Avoid drinking grapefruit juice or eating grapefruit while taking MEDROL 16MG TABLET as it may lead to unwanted side effects.

Overdosage:

If you or anyone else accidentally took more MEDROL 16MG TABLET, consult your doctor immediately or visit the nearby hospital straight away.

SYNOPSIS

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