INTRODUCTION ABOUT LOSACAR A TABLET

LOSACAR A TABLET is a combination of Amlodipine and Losartan, which belongs to the group of medicines called Anti-hypertensive agents. It is used primarily in the management of hypertension (to lower blood pressure) in stage 2 hypertensive patients. This medicine is used in adults and children the age of 6 years and above.

Hypertension is a condition where pressure is exerted on the walls of the blood vessels inside the body, making the heart difficult to pump blood out to other parts of the body. This leads to symptoms such as early morning headaches, nosebleeds, irregular heart rhythms, vision changes, and buzzing in the ears. More severe forms may cause chest pain and muscle tremors. If left unmanageed, hypertension can cause persistent chest pain (also called angina), heart attacks, heart failure, and an irregular heartbeat, which can also get life-threatening.

Before taking this medicine, inform your doctor if you are allergic (hypersensitive) to the medicine or any ingredients present in it, or if you have, liver, kidney or heart problems.

Pregnant and breastfeeding women should consult their doctors before receiving this medicine.

The most common side effects are headache, muscle cramps, nausea, vomiting and diarrhoea. Consult your doctor for advice if any of the above side effects worsen or persists for a longer duration.

USES OF LOSACAR A TABLET

• Used to manage essential hypertension

HOW LOSACAR A TABLET WORKS

LOSACAR A TABLET is a combination of Amlodipine and Losartan where Amlodipine is a calcium channel blocker and losartan belong to angiotensin II receptor blocker they collectively function as a vasodilator. It acts by widening of the blood vessels as a result it enhances the blood flow to all parts of the body easily, thereby causing reduction in blood pressure level.

DIRECTIONS FOR USE

Take LOSACAR A TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF LOSACAR A TABLET

HOW TO MANAGE SIDE EFFECTS

Nausea and Vomiting:

Take this medicine with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food.

Diarrhoea:

Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for managing diarrhoea. Consult your doctor if the symptom did not improve.

Abdominal pain:

Try to rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. If the symptom does not improve, contact your doctor.

Headache:  

Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the head if required. Do not consume too much of alcohol. Consult your doctor if the symptom did not improve.

Constipation:

Eat plenty of fibre rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly.

Diarrhoea:

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug - Drug interactions:

Inform your physician if you are taking any of the following medicine:

• other diuretics that contain amiloride (Ex. spironolactone, heparin)
• other drugs for high blood pressure (Ex. Ace inhibitors such as captopril, lisinopril)
• tricyclic anti-depressants such as (Ex. amitriptyline, amoxapine)
• medicines to manage HIV (Ex. ritonavir, indinavir)
• non-steroidal anti-inflammatory drugs (Ex. indomethacin including Cox-2 inhibitors)
• antibiotics (Ex. clarithromycin, erythromycin)
• anti-fungal (Ex. ketoconazole, itraconazole)
• cholesterol lowering medicine (Ex. simvastatin)
• immunosuppressants (Ex. cyclosporin)
• used to manage heart disorders (Ex. verapamil, diltiazem)
• St. john’s wort (hypericum perforatum)
• antipsychotic medicine (Ex. clozapine)
• skeletal muscle relaxant (Ex. baclofen)
• cancer medicine (Ex. amifostine)

B. Drug - Food interaction:

Grapefruit should be avoided while taking LOSACAR A TABLET as, it may increase the blood pressure level.

Overdosage:

If you or anyone else accidentally took too much of this medicine, consult your doctor immediately. Symptoms include low blood pressure, which could lead to feeling dizzy or light headedness.

SYNOPSIS

MORE INFORMATION

• Keep out of reach of children
• Store in room temperature