INTRODUCTION

LANOXIN 0.25MG contains Digoxin which belongs to the group of medicines called Cardiac glycosides. It is used in the management of arrhythmias (irregular heartbeat, which causes the heart to skip a beat or beat at the wrong speed) and heart failure. Heart failure is a chronic condition where the heart doesn’t pump sufficient blood to other parts of the body, which is generally characterized by symptoms such as shortness of breath, fatigue, weakness, rapid or irregular heartbeat and swelling in the legs, ankles or feet.

LANOXIN 0.25MG is not recommended for use in patients with serious heart problems (such as stokes-Adams attacks (condition where you suddenly feel faint and can pass out due to changes in heart rate) or irregular heartbeat due to cardiac glycoside intoxication).

Before taking LANOXIN 0.25MG, inform your doctor if you have beri-beri disease (which occurs due to vitamin B1 deficiency), severe lung disease, reduced renal function or liver failure. Along management with LANOXIN 0.25MG, your doctor might advise you to take regular blood test to determine the amount of digoxin in your blood and to check the status of the kidney function, especially in patients with kidney disorders.

LANOXIN 0.25MG should be used with caution in pregnant and breastfeeding women. Also, it should be used with caution in children and adolescents (below 18 years of age) and in elderly patients (aged 65 years and above).

The most common side effects of taking LANOXIN 0.25MG are nausea, vomiting, diarrhea, abnormal heartbeat and dizziness. Consult your doctor if any of the side effect gets worse.

USES OF LANOXIN 0.25MG

Manages,

• arrhythmia
• heart failure

HOW LANOXIN 0.25MG WORKS

LANOXIN 0.25MG works by increasing the force of contraction of the heart by reversibly inhibiting an enzyme (responsible for controlling the movement of ions into the heart), which leads to correction of irregular heartbeats and strengthening of contraction force, thus helps to manage irregular heartbeat and heart failure.

DIRECTIONS FOR USE

Take LANOXIN 0.25MG as directed by your physician. It can be taken with or without meals. Swallow the medicine as whole with a sip of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and health condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF LANOXIN 0.25MG

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Take LANOXIN 0.25MG with meals. Stick to simple meals while taking this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Consult your doctor if the symptom does not improve.  

Diarrhea:

Drink lot of fluids, such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Try to avoid taking any medicine on your own to manage diarrhea and consult your doctor if the symptom gets worse.

Dizziness:

Lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol and drugs. Consult your doctor if the symptom gets worse.

WARNING & PRECAUTIONS

INTERACTIONS

Before taking LANOXIN 0.25MG, inform your doctor if you are taking any of the following medicines:

• angiotensin receptor blockers (Ex. telmisartan, irbesartan), angiotensin-converting-enzyme inhibitors (Ex. captopril, enalapril) and nifedipine, verapamil, felodipine, carvedilol, prazosin and diuretics (Ex. chlorothiazide, chlorthalidone) and beta-blockers Ex. atenolol, metoprolol, esmolol (used to manage high blood pressure)

• lithium, nefazodone, st. john’s wort, bupropion (used to manage depression)
• indomethacin and corticosteroids such as dexamethasone, hydrocortisone (used to provide relief from inflammation)
• carbenoxolone (used to manage digestive tract ulcers)
• other medicines used to prevent and manage arrhythmias (Ex. amiodarone, flecainide, propafenone, quinidine, dronedarone)
• canagliflozin, acarbose (used to manage type 2 diabetes mellitus)
• neomycin, penicillamine, rifampicin, erythromycin, clarithromycin, tetracycline, gentamicin, trimethoprim (antibiotics used to manage bacterial infections)
• telaprevir or daclatasvir, simeprevir, velpatasvir (used with or without other medicines to manage hepatitis C)
• flibanserin (used to manage low sexual desire in women who have not gone through menopause)
• sennosides (used to manage constipation)
• isavuconazole, itraconazole (used to manage fungal infections)
• ivacaftor (used to manage cystic fibrosis)
• spironolactone (medicine used to manage heart failure)
• alprazolam (used to manage anxiety)
• indomethacin (used to manage inflammation)
• quinine (used to prevent malaria infection)
• propantheline (used to prevent muscle spasms)
• mirabegron (used to manage overactive bladder)
• atorvastatin, colestyramine (used to lower blood cholesterol)
• cyclosporine (used to prevent organ rejection after transplantation)
• epoprostenol (used to manage pulmonary arterial hypertension)
• tolvaptan, conivaptan (used to manage low blood sodium levels)
• ritonavir (used to manage HIV infection)
• ranolazine, tiapamil (used to manage chest pain)
• lapatinib (used to manage breast cancer)
• ticagrelor (used to prevent heart attack or stroke)
• vandetanib (used to manage certain cancers of the thyroid gland)
• venetoclax (used to manage patients with chronic lymphocytic leukemia)
• vemurafenib (used to manage adult patients with a type of cancer called melanoma)
• proton pump inhibitors (PPIs) (used to relieve symptoms of acid reflux) Ex. lansoprazole, omeprazole
• medicines used to manage pain and inflammation such as non-steroidal anti-inflammatory drugs (Ex. ibuprofen, naproxen), and COX-2 inhibitors (Ex. celecoxib, rofecoxib)
• antacids (used to manage gastric acidity) Ex. aluminum hydroxide and magnesium carbonate.
• bulk-forming laxatives (used to manage constipation) Ex. psyllium, polycarbophil
• kaolin-pectin (used to manage diarrhoea)
• cytostatic drugs such as epirubicin, bleomycin (used as chemotherapy for cancer management)
• metoclopramide (used to manage nausea and vomiting)
• sulfasalazine (used to manage inflammatory diseases of the intestine)
• adrenaline (used to manage severe allergic reactions)
• salbutamol (used to manage asthma)
• phenytoin (used to manage epilepsy)
• supplemental enteral nutrition (used to augment nutrition)
• intravenous calcium (used to manage calcium deficiency)
• sympathomimetics (used to manage heart attack and low blood pressure) Ex. amphetamine, benzylpiperazine 

B. Drug - Food interactions:

Avoid having foods high in fiber (dietary fiber) while taking LANOXIN 0.25MG as it may reduce the absorption of this medicine in the body

Over dosage:

If you or anyone else accidentally take too much of LANOXIN 0.25MG, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of LANOXIN 0.25MG are heart rhythm disturbances, gastrointestinal symptoms (such as loss of appetite, nausea and vomiting) dizziness, fatigue, various neurological disturbances including visual disturbances and non-heart related symptoms (such as weakness and general feeling of being unwell).  

SYNOPSIS

MORE INFORMATION

• Keep LANOXIN 0.25MG out of reach of children
• Store LANOXIN 0.25MG at room temperature