ISOLAZINE Tablet 15's
HYDRALAZINE 37.5 mg + ISOSORBIDE DINITRATE 20 mg
₹ 188.00
₹210
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About this item
INTRODUCTION ABOUT ISOLAZINE TABLET
ISOLAZINE TABLET is a combination of Hydralazine and Isosorbide dinitrate which belongs to the group of medicines called Vasodilators. It is used to manage heart failure along with standard therapy in patients to improve survival, delay hospitalization for heart failure and to improve patient-reported functional status.
Heart failure is defined as a progressive clinical disorder where your heart is unable to pump sufficient blood to meet the body’s metabolic needs, characterized by shortness of breath and extreme tiredness.
During course of the management your doctor might regularly monitor your blood pressure to avoid any untoward side effects. The safety and effectiveness of ISOLAZINE TABLET in children have not been established.
Before taking ISOLAZINE TABLET, inform your doctor if you have any kidney, heart, lung or liver problems, too much sweating, fluid loss, vomiting or diarrhea or if you consume alcohol.
ISOLAZINE TABLET is not studied in pregnant and breastfeeding women, so consult your doctor before taking it. The most common side effects of taking ISOLAZINE TABLET are headache and dizziness. Consult your doctor if any of the side effects worsen.
USES OF ISOLAZINE TABLET
- Manage heart failure
HOW ISOLAZINE TABLET WORKS
ISOLAZINE TABLET helps in the management of heart failure, where hydralazine relaxes the smooth muscles of arteries and isosorbide dinitrate acts by releasing nitric oxide and subsequently activating guanylyl cyclase and ultimately relaxes smooth muscles of both arteries and veins.
DIRECTIONS FOR USE
Take ISOLAZINE TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF ISOLAZINE TABLET
COMMON
- headache
- dizziness
RARE
Stop taking ISOLAZINE TABLET and consult your doctor immediately if you experience any of the following side effects:
- allergic reaction (signs include rash, hives, itching, red, swollen, blistered or peeling skin, wheezing, tightness in the chest or throat, difficulty breathing, swallowing or talking, unusual hoarseness or swelling of the mouth, face, lips, tongue or throat)
- lupus-like rash on the cheeks or other body parts, easy sunburn, muscle or joint pain, chest pain or breathlessness or swelling in the arms or legs
- low blood pressure (very bad dizziness or passing out)
- fever
- insufficient oxygen supply to heart muscle and angina (chest pain or pressure or a fast heartbeat)
- peripheral neuritis (numbness, prickling and tingling sensation)
HOW TO MANAGE SIDE EFFECTS
Headache:
Drink ample amount of water. Get adequate rest. Try to be relaxed and stress free. Ask your doctor before taking any medicine for headache.
Dizziness:
When you start taking ISOLAZINE TABLET, you may feel dizzy. If this happens, resting or lying down for some time can help. Rise slowly after sitting or lying down. Be careful while going up and down stairs. Consult your doctor if you experience persistent dizziness.
WARNING & PRECAUTIONS
PREGNANCY
ISOLAZINE TABLET is not studied in pregnant women. Consult your doctor before taking it.
BREASTFEEDING
ISOLAZINE TABLET is not studied in breastfeeding women. Consult your doctor before taking this medicine as it is not known if it passes into breast milk.
DRIVING AND USING MACHINES
Do not drive or use any machines until you see how ISOLAZINE TABLET affects you.
ALCOHOL
Avoid consumption of alcohol during management with ISOLAZINE TABLET as it may increase the risk of vasodilating effects of this medicine.
KIDNEY
ISOLAZINE TABLET is not studied in patients with kidney impairment. Consult your doctor before taking it.
LIVER
ISOLAZINE TABLET is not studied in patients with liver impairment. Consult your doctor before taking it.
ALLERGY
Do not take ISOLAZINE TABLET if you are allergic to Hydralazine or Isosorbide dinitrate.
HEART DISEASE
ISOLAZINE TABLET should be used with caution in patients with hypertrophic cardiomyopathy. Consult your doctor before taking it.
OTHERS
Before taking ISOLAZINE TABLET, inform your doctor if you:
- have too much sweating, fluid loss, vomiting or diarrhea
Use in pediatrics:
Safety and effectiveness of ISOLAZINE TABLET in children and adolescents (aged less than 18 years) have not been established. Consult your child’s doctor for advice.
Use in geriatrics:
ISOLAZINE TABLET should be used with caution in elderly patients. Consult your doctor before taking it.
INTERACTIONS
A. Drug - Drug interactions:
Before taking ISOLAZINE TABLET, inform your doctor if you are taking any of the following medicines:
- medicines used to manage erectile dysfunction (Ex. avanafil, sildenafil, tadalafil, vardenafil)
- riociguat (used to manage high blood pressure in the vessels that carry blood to the lungs)
Overdosage:
If you or anyone else accidentally took too much of ISOLAZINE TABLET, contact your doctor immediately. Symptoms of overdose include headache, confusion, fast heartbeat, generalized skin flushing, reduced cardiac output, low blood pressure, irregular heartbeat and shock.
SYNOPSIS
| Drug | : | Hydralazine, Isosorbide dinitrate |
| Pharmacological Category | : | Vasodilators |
| Therapeutic Indication | : | As adjunct to standard management in heart failure |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep ISOLAZINE TABLET out of reach of children
- Store at room temperature
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