INTRODUCTION ABOUT INDOCAP SR 75MG CAPSULE

INDOCAP SR 75MG CAPSULE contains Indomethacin, which belongs to the group of medicines called Non-Steroidal Anti-Inflammatory Drugs. It is used to reduce swelling and manage moderate to severe inflammatory diseases of the joints (such as rheumatoid arthritis, osteoarthritis and degenerative hip disease), pain & stiffness in the backbone (ankylosing spondylitis).

It also manages sprains & strains, post-operative pain, lower back pain, pain due to periods, gout (joint pain), and acute painful shoulder (such as bursitis, tendinitis). During management with INDOCAP SR 75MG CAPSULE, your doctor might advise you to take certain tests.

INDOCAP SR 75MG CAPSULE is not recommended for use in patients with angioneurotic oedema (condition marked by swelling of the face, lips, tongue, or throat), have or had signs of peptic ulcer/bleeding in the stomach/intestine (black tarry stools), nasal obstruction (due to nasal polyps), severe liver, kidney, or heart problems.

Before taking INDOCAP SR 75MG CAPSULE inform your doctor if you have a history of high blood pressure or congestive heart failure, bleeding or blood clotting disorder, mental health problem, epilepsy, Parkinson’s Disease (tremor, stiffness and shuffling) or severe infection.

Also inform your doctor if you have fluid retention which may be caused by diseases of the heart or kidneys, history of asthma, gastrointestinal diseases (ulcerative colitis or Crohn’s disease), systemic lupus erythematosus (SLE), diabetes, problem with the circulation in the legs, decreased amount of fluid in body or are going to have surgery.

Avoid consumption of alcohol during management with INDOCAP SR 75MG CAPSULE. INDOCAP SR 75MG CAPSULE is not recommended for use in pregnant women (especially during the last 3 months of pregnancy) and in breastfeeding women.

This medicine is not recommended for use in children aged below 14 years. It should be used with caution in elderly patients. The most common side effect of taking INDOCAP SR 75MG CAPSULE is a mild headache. Contact your doctor if the symptoms worsen.

USES OF INDOCAP SR 75MG CAPSULE

It is used to reduce swelling and manage:

• moderate to severe inflammatory diseases of the joints (such as rheumatoid arthritis, osteoarthritis and degenerative hip disease)
• pain & stiffness in the backbone (ankylosing spondylitis)
• sprains & strains (such as acute muscle and bone disorders)
• lower back pain
• pain & swelling following muscle/ bone surgery
• pain due to menstruation
• gout (joint pain)
• acute painful shoulder (such as bursitis, tendinitis)

HOW INDOCAP SR 75MG CAPSULE WORKS

INDOCAP SR 75MG CAPSULE works by managing the function of enzyme cyclooxygenase-1 and 2 which leads to the stopping of prostaglandins synthesis (chemical substances responsible for pain & inflammation) that results in reduced inflammatory reactions and relief from pain.

DIRECTIONS FOR USE

Take INDOCAP SR 75MG CAPSULE as advised by your physician. Swallow INDOCAP SR 75MG CAPSULE with a glass of water/milk, with or immediately after food. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.

SIDE EFFECTS OF INDOCAP SR 75MG CAPSULE

HOW TO MANAGE SIDE EFFECTS

Headache:

Apply a hot or cold-water bag on your head. Try to rest in a quiet and dark room. Massage on the scalp or head with mild pressure. Consult your doctor if symptoms do not improve.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug - Drug interactions:

Before taking INDOCAP SR 75MG CAPSULE, inform your doctor if you are taking any of the following medicines:

• other non-steroidal anti-inflammatory drugs (medicines used to reduce inflammation and relieve pain) Ex. aspirin, naproxen, celecoxib, diflunisal, methotrexate
• quinolone antibiotics (medicine used to manage infections Ex. ciprofloxacin)
• medicines used for blood thinning or manage blood clotting (Ex. warfarin, clopidogrel)
• medicines used to manage depression, such as selective serotonin reuptake inhibitors (Ex. fluoxetine), haloperidol, lithium (a medicine used to manage mental illness)
• medicines used to manage diabetes (Ex. metformin, gliclazide)
• phenytoin (medicine used to manage epilepsy)
• diazepam (a medicine used to manage anxiety, alcohol withdrawal, seizures and muscle spasm)
• medicines used to manage high blood pressure such as alpha-blockers (Ex. prazosin), beta blockers (Ex. atenolol), ACE inhibitors (Ex. lisinopril), angiotensin II receptor antagonists (Ex. valsartan), hydralazine or nifedipine, diuretics (Ex. triamterene, furosemide), thiazides (Ex. bendroflumethiazide), cardiac glycosides (used to manage heart failure, Ex. digoxin)
• medicines used to manage HIV infection (Ex. zalcitabine, zidovudine or ritonavir)
• medicines used to suppress the immune system and manage graft rejection (Ex. ciclosporin, tacrolimus or muromonab-CD3)
• antacids (medicines used to manage stomach acid and heartburn, Ex. aluminium hydroxide, magnesium hydroxide)
• corticosteroids (used to manage various allergic and inflammatory disorders, Ex. prednisolone)
• methotrexate or cyclophosphamide (medicines used to manage rheumatoid arthritis and certain types of cancer)
• desmopressin (medicine used to manage diabetes insipidus and urinary incontinence)
• mifepristone (a medicine used to terminate pregnancy)
• baclofen (a medicine used as a muscle relaxant)
• pentoxifylline (used to manage blood vessel disease and leg ulcers)
• probenecid (a medicine used to manage gout)
• tiludronic acid (a medicine used to manage Paget’s disease of bone)

Overdosage:

If you or anyone else has accidentally taken too much of INDOCAP SR 75MG CAPSULE, consult your doctor immediately or visit the nearby hospital. Signs and symptoms of overdose may include headache, nausea, vomiting, stomach pain, bleeding in the stomach/intestines, diarrhoea, disorientation, excitement, coma, drowsiness, dizziness, ringing/buzzing in the ears, fainting, fits/seizures, acute kidney/renal failure, liver damage.

SYNOPSIS

MORE INFORMATION

• Keep out of reach of children
• Store in a dry place below 25°C