INTRODUCTION

HEPAKIND contains Ursodeoxycholic acid (also known as Ursodiol) which is a Gallstone dissolving agent. It is used to dissolve gall bladder stones (made up of cholesterol) and prevents them from forming back. It can also be used to manage a type of liver disease called primary biliary cholangitis. Primary biliary cholangitis (also known as primary biliary cirrhosis) is a long-term liver disease in which the tubes carrying a digestive fluid called bile (bile ducts) are injured, inflamed, and permanently damaged. As a result, it can cause yellow or white bumps under the skin or eyes, dark urine, and abnormally swollen stomach with pain with frequent nausea, weight loss and tiredness. HEPAKIND can also be used to manage liver and biliary diseases caused due to cystic fibrosis (an inherited disorder that affects major organs) in children aged between 6-18 years.

HEPAKIND is a liver protectant medication. It works by reducing cholesterol levels in the blood which is dissolving the gall bladder stones made up of cholesterol. It also improves liver functions by protecting the liver cells against the injury caused by toxic bile acid.

Before taking HEPAKIND inform your doctor, if you have any other liver problems apart from gall stones and biliary cirrhosis. While taking HEPAKIND, your doctor would regularly monitor your liver function to access how you respond to the management. HEPAKIND is not recommended for use in pregnant women. Women of childbearing age should use a suitable non-hormonal contraceptive method like condemn or copper-IUD to avoid getting pregnant. The most common side effect of HEPAKIND is pasty stools. Consult your doctor if it bothers you.

USES OF HEPAKIND

• Manages primary biliary cholangitis
• Manages and prevents gall bladder stones
• Manages liver and biliary diseases caused due to cystic fibrosis in children aged between 6-18 years

HOW HEPAKIND WORKS

HEPAKIND is a liver protectant medication. It works by reducing cholesterol levels in the blood by decreasing its production in the liver and by inhibiting its absorption in the intestines. As a result, it slowly breaks down the gall bladder stones made up of cholesterol. It also improves liver functions by protecting the liver cells against the injury caused by toxic bile acid, thereby improving liver health in diseased patients.

DIRECTIONS FOR USE

HEPAKIND should only be used under medical supervision. Swallow HEPAKIND with a glass of water and do not crush or chew it. Your doctor will decide the correct dose for you depending upon your age, body weight and disease condition. You can take HEPAKIND after a meal with a glass of milk or a small snack.

SIDE EFFECTS OF HEPAKIND

HOW TO MANAGE SIDE EFFECTS

Pasty stools or diarrhea:

Drink lots of fluids, such as water or juice, to avoid dehydration. Take plenty of rest. Do not take any medicines without speaking to a doctor.

WARNING & PRECAUTIONS

INTERACTIONS

Before taking HEPAKIND, inform your doctor, if you are taking any of the following medicine:

• medicines that can bind to cholesterol and inactive them (Ex. bile acid sequestrants (such as colestipol, colestyramine))
• medicines used to neutralize stomach acid (such as antacids containing aluminium hydroxide or smectite)
• ciprofloxacin (used to manage bacterial infection)
• dapsone (used to manage leprosy)
• nitrendipine (a medicine used to manage high blood pressure)
• ciclosporin (used to suppress immune function and prevent graft rejection)
• oral contraceptives (birth control pills) Ex. norethindrone
• oestrogens (used to manage menopause, PMS, and other hormonal conditions in females) Ex. Estradiol

Overdosage:

If you or anyone else accidentally take excess of HEPAKIND, consult your doctor immediately or visit the nearby hospital. Symptom of overdose can be prolonged diarrhea.

SYNOPSIS

MORE INFORMATION

• Keep out of reach of children
• Do not store above 25°C