INTRODUCTION ABOUT GLUCONORM G1 FORTE TABLET

GLUCONORM G1 FORTE TABLET is used to manage type 2 diabetes mellitus when diet, exercise and the single agent does not result in adequate glycemic control. It is a combination of Glimepiride and Metformin which belongs to a group of medicines called Antidiabetic agents. Glimepiride lowers blood sugar by causing the pancreas to produce more insulin and helps the body to use insulin efficiently. Metformin reduces the total amount of sugar released into the blood by the liver.

Along management with GLUCONORM G1 FORTE TABLET follow regular exercise and diet plan as advised by your doctor to achieve better results. Before taking GLUCONORM G1 FORTE TABLET inform your doctor if you have type 1 diabetes mellitus, diabetic ketoacidosis, severe liver or kidney disease, acute heart problems. Inform your doctor if you are pregnant or breastfeeding. It is not suitable for use in children and adolescents under 18 years of age.

Avoid consumption of alcohol during management with GLUCONORM G1 FORTE TABLET as it may increase or decrease the blood sugar lowering action of GLUCONORM G1 FORTE TABLET and increases the risk of lactic acidosis. The most common side effects of taking GLUCONORM G1 FORTE TABLET are taste disturbance, diarrhea or stomach ache. Contact your doctor if any of the symptoms worsen.

USES OF GLUCONORM G1 FORTE TABLET

• Used to manage type 2 diabetes mellitus (when diet, exercise and the single agent does not result in adequate glycemic control)

HOW GLUCONORM G1 FORTE TABLET WORKS

GLUCONORM G1 FORTE TABLET controls blood glucose levels, where Glimepiride works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin works by lowering glucose production in the liver, delaying glucose absorption from intestine, and increasing the body's sensitivity to insulin.

DIRECTIONS FOR USE

• Take GLUCONORM G1 FORTE TABLET as advised by your physician
• Swallow GLUCONORM G1 FORTE TABLET with a glass of water. Do not crush or chew the medicine
• Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition
• Do not stop taking GLUCONORM G1 FORTE TABLET without informing your doctor.  

SIDE EFFECTS OF GLUCONORM G1 FORTE TABLET

Common side effects of GLUCONORM G1 FORTE TABLET:

• taste disturbance
• diarrhea
• stomach pain
• loss of appetite

Stop taking GLUCONORM G1 FORTE TABLET and contact your doctor immediately if you experience any of the following side effects:

• lactic acidosis
• inflammation of the liver which may result in jaundice (yellowing of skin or eyes)
• severe allergic reactions (such as skin rash, hives, and increased sensitivity to sun, inflammation of blood vessels which may develop into serious reactions with difficulty in breathing, fall in blood pressure and sometimes progressing to shock)
• severe low blood sugar levels

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking GLUCONORM G1 FORTE TABLET inform to your doctor,  if you are taking any of these medicines:

• Sulphonylureas (Ex. glibenclamide, insulin)
• Anabolics
• Anticoagulants (Ex. Warfarin)  
• Anticonvulsants (Ex. Fenfluramine, Phenytoin)
• NSAIDs (Ex. Phenylbutazone, azopropazone, oxyphenbutazone)
• Class 1a anti-arrhythmic agent (Ex. Disopyramide)
• Fibrates (Ex. fenofibrate, nicotinic acid, colesevelam)
• Angiotensin-converting enzyme (Ex. captopril, lisinopril)
• Diuretics (Ex. furosemide, chlorthalidone, hydrochlorothiazide or diazoxide)
• Monoamine oxidase inhibitors (Ex. isocarboxazid, selegiline and chlorpromazine)
• Antigout agents (Ex. Allopurinol, probenecid, sulfinpyrazone)
• Alkylating agents (Ex. Cyclophosphamide, ifosfamide, trofosfamide)
• Tetracyclines (Ex. minocycline, doxycycline, chloramphenicol, fluconazole, miconazole
• Quinolones (Ex. moxifloxacin, ciprofloxacin, clarithromycin, rifampicin
• Tritoqualine, glucocorticoids (Ex. beclomethasone, hydrocortisone)
• Hemorrheologic agents (Ex. Pentoxifylline)
• Sulfonamides (Ex. sulfamethoxazole)
• Androstane class (Ex. testosterone)
• Natural or synthetic (Ex. oestrogens, progestogens)
• Sympatholytics (Ex. clonidine, methyldopa)
• Hormones (Ex. Levothyroxine)  
• Adrenaline and sympathomimetics (Ex. phenylephrine, norepinephrine)
• Laxatives (Ex. bisacodyl)
• Antidiabetics (Ex. Glucagon)
• Barbiturates (Ex. pentobarbital, amobarbital)
• Carbonic anhydrase inhibitors (Ex. Acetazolamide)

Overdosage:

If you or anyone else takes too much of GLUCONORM G1 FORTE TABLET, contact your doctor immediately or go to a nearest hospital straight away. Overdosage symptoms of GLUCONORM G1 FORTE TABLET includes risk of low blood sugar levels. Symptoms of lactic acidosis include vomiting, bellyache with muscle cramps, general feeling of not being well with severe tiredness, reduced body temperature, low heartbeat, and difficulty in breathing.

SYNOPSIS