INTRODUCTION ABOUT EPTOIN ER 300MG TABLET

EPTOIN ER 300MG TABLET contains Phenytoin which belongs to the group of medicines called Anti-epileptic drugs. It is used to manage certain forms of epilepsy (fits or seizures) during or after brain surgery or severe head injury. Epilepsy is defined by the occurrence of at least two unprovoked seizures with or without fits (strong, involuntary contractions of the voluntary muscles) parted by at least 24 hours. A seizure results from an excessive discharge of specific nerve cells and it is characterized by changes in electrical activity (detected by electroencephalogram (EEG). EPTOIN ER 300MG TABLET is also used to manage trigeminal neuralgia (facial nerve pain).

During management with EPTOIN ER 300MG TABLET, your doctor might ask you to take several blood tests, to monitor any side effects, and to check the amount of phenytoin in blood to make dose adjustments. You should brush and floss your teeth and see a dentist regularly while taking EPTOIN ER 300MG TABLET, to manage overgrowth of gums.

Before taking EPTOIN ER 300MG TABLET, inform your doctor if you have any liver or kidney problems, or porphyria. Avoid consumption of alcohol while taking EPTOIN ER 300MG TABLET as it may affect its concentration in the blood. EPTOIN ER 300MG TABLET should be used with caution in pregnant women only if advised by the doctor as it may cause harm to the unborn baby. Women of childbearing potential should use a suitable non-hormonal contraceptive method to avoid getting pregnant while taking EPTOIN ER 300MG TABLET. It is not recommended for use in breastfeeding women.

Patients taking EPTOIN ER 300MG TABLET may have self-harming thoughts. If at any time you have these thoughts, immediately consult your doctor. EPTOIN ER 300MG TABLET should be cautiously used in children and in elderly patients, particularly with kidney or liver problems. The most common side effects of taking EPTOIN ER 300MG TABLET are irregular or involuntary eye movements, slurred speech, drowsiness, problems with movement and balance, decreased coordination and confusion. Consult your doctor if any of the side effects worsen.

USES OF EPTOIN ER 300MG TABLET

It is used to:

• Manage certain forms of epilepsy (that occur during or after brain surgeries or severe head injury)
• Manage trigeminal neuralgia (facial nerve pain)

HOW EPTOIN ER 300MG TABLET WORKS

EPTOIN ER 300MG TABLET controls seizures (fits) by reducing the abnormal activity of the nerve cells in the brain. It also reduces the pain by blocking the transmission of pain signals across the nervous system thus reducing the symptoms of trigeminal neuralgia.

DIRECTIONS FOR USE

Take EPTOIN ER 300MG TABLET as advised by your physician. Swallow EPTOIN ER 300MG TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will determine the correct dose and duration for you depending on your age, body weight and disease condition. Do not stop taking EPTOIN ER 300MG TABLET unless your doctor advises you to stop.

SIDE EFFECTS OF EPTOIN ER 300MG TABLET

HOW TO MANAGE SIDE EFFECTS

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking EPTOIN ER 300MG TABLET, inform your doctor if you are taking any of the following medicines:

• medicines used to manage heart and circulation problems (Ex. amiodarone, digoxin, furosemide, reserpine, warfarin, mexiletine, disopyramide and calcium channel blockers such as diltiazem, nicardipine, nifedipine, nimodipine, verapamil)
• medicines used to lower blood cholesterol (Ex. atorvastatin, fluvastatin and simvastatin)
• medicines used to manage epilepsy (Ex. oxcarbazepine, carbamazepine, topiramate, phenobarbital, lacosamide, lamotrigine, sodium valproate and valproic acid and succinimides such as ethosuximide, vigabatrin)
• medicines used to manage fungal infections (Ex. amphotericin B, fluconazole, itraconazole, ketoconazole, miconazole, posaconazole, voriconazole)
• medicines used to manage tuberculosis and other bacterial infections (Ex. isoniazid, chloramphenicol, sulphonamides such as sulfadiazine, rifampicin, doxycycline, clarithromycin, sulfamethoxazole trimethoprim, ciprofloxacin)
• medicines used in the management of HIV infection (Ex. indinavir, ritonavir, efavirenz, fosamprenavir, saquinavir)
• medicines used to manage stomach ulcers (Ex. omeprazole, sucralfate, cimetidine and antacids)
• theophylline (used to manage asthma and bronchitis)
• medicine used to manage pain (Ex. aspirin)
• medicines used to manage inflammation (Ex. prednisolone, dexamethasone)
• medicines used for sleeplessness, depression and psychiatric disorders (Ex. chlordiazepoxide, clozapine, diazepam, disulfiram, fluoxetine, methylphenidate, paroxetine, phenothiazines such as chlorpromazine, trazodone, tricyclic antidepressants such as amitriptyline, fluvoxamine, quetiapine, sertraline)
• tolbutamide (used to manage high blood sugar)
• medicines used to manage pregnancy (Ex. estradiol, desogestrel)
• medicines used to suppress the immune system and manage graft rejection (Ex. ciclosporin, tacrolimus)
• medicines used to manage cancer (Ex. capecitabine, carboplatin, bleomycin, cisplatin, doxorubicin, methotrexate, fluorouracil)
• medicines used to relax the muscles (Ex. rocuronium, vecuronium)
• methadone (medicine used to manage severe pain)
• medicines used to control blood clotting (Ex. rivaroxaban, dabigatran, apixaban, edoxaban, ticagrelor)
• non-prescription medicines (Ex. folic acid (manages folate deficiency), st. john’s wort (manages depression) and vitamin D (manages osteoporosis))  

Overdosage:

If you or anyone else accidentally take too much of EPTOIN ER 300MG TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of EPTOIN ER 300MG TABLET include nystagmus (rapid eye movements), ataxia (clumsy movements), dysarthria (trouble speaking), shaking, hyperreflexia (overactive bodily reflexes like twitching), lethargy, slurred speech, blurred vision, nausea, vomiting, low blood pressure, low heart rate.

SYNOPSIS

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