INTRODUCTION ABOUT DOLOWIN SR TABLET

DOLOWIN SR TABLET is used to relieve pain and reduce redness and swelling (inflammation) in patients suffering from osteoarthritis (arthritis of the joints) which commonly occurs in patients over the age of 50 and causes the loss of the cartilage and bone tissue next to the joint.

It also manages rheumatoid arthritis (an autoimmune disorder that causes chronic inflammation of the joints) and ankylosing spondylitis (arthritis of the spine which can lead to fusion of the vertebrae).

DOLOWIN SR TABLET is not recommended for use in patients with a stomach ulcer, severe kidney disease, heart disease (heart attack), cerebrovascular disease (such as stroke or transient ischemic attack) or blockage of blood vessels to the heart or brain, peripheral arterial disease (poor blood circulation to extremities of the body), severe liver failure and blood clotting disorders.

Before taking DOLOWIN SR TABLET, inform your doctor if you have diabetes, raised cholesterol or triglyceride levels, a rare inherited disorder like porphyria, systemic lupus erythematous or other connective tissue disorders and if you are recovering from major surgery or have a habit of smoking.

DOLOWIN SR TABLET is not recommended for use in pregnant and breastfeeding women unless advised by the doctor. Consult your doctor before taking this medicine.

DOLOWIN SR TABLET is not recommended for use in children and adolescents (under 18 years of age). DOLOWIN SR TABLET should be used with caution in elderly patients due to the increased risk of serious side effects.

The most common side effects of taking DOLOWIN SR TABLET are dizziness, nausea and diarrhoea. Consult your doctor if any of the side effects worsen.

USES OF DOLOWIN SR TABLET

DOLOWIN SR TABLET is used to relieve pain and reduce redness and swelling (inflammation) in patients suffering from:

• osteoarthritis (arthritis of the joints)
• rheumatoid arthritis (an autoimmune disease that causes chronic inflammation of joints)
• ankylosing spondylitis (arthritis of the spine)

HOW DOLOWIN SR TABLET WORKS

DOLOWIN SR TABLET works by exhibiting anti-inflammatory and painkiller properties by blocking the enzyme cyclo-oxygenase, which is involved in the production of prostaglandins which are responsible for causing pain and inflammation (swelling).

DIRECTIONS FOR USE

Take DOLOWIN SR TABLET as advised by your physician. It can be taken with or after food.

For Tablet, Capsule: Swallow DOLOWIN SR TABLET with a glass of water. Do not crush or chew the medicine.

For Dispersible Tablet: Disperse the medicine in the specified quantity of water as mentioned on the label. Consume the medicine immediately after reconstitution.

Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.

SIDE EFFECTS OF DOLOWIN SR TABLET

HOW TO MANAGE SIDE EFFECTS

Nausea or Vomiting:

Take this medicine with or just after meals. Stick to simple meals. Try to avoid oil-rich or spicy foods, sugary snacks and drinks. Try to drink liquid slowly along with your meals or in between meals. Consult your doctor if your symptom is not improving.

Constipation:

Take fibre-rich foods in your diet such as fresh fruits, vegetables and whole grain cereals and drink plenty of fluids. Exercise more regularly (such as daily walk) and stay active. Consult your doctor if the symptom does not improve.

Diarrhoea:

Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for managing diarrhoea. Consult your doctor if the symptom did not improve.  

Stomach pain:

Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heating pad on your stomach. Do not self-manage on your own and consult your doctor if the symptom did not improve on their own.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume alcohol as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug - Drug interactions:

Before taking DOLOWIN SR TABLET, inform your doctor if you are taking any of the following medicines:  

• medicines used to manage depression (Ex. citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine and sertraline) or lithium
• medicines used to manage heart failure and irregular heartbeats (Ex. digoxin)
• medicines used to manage high blood pressure (Ex. enalapril, lisinopril, losartan, candesartan, hydralazine, methyldopa, clonidine, propranalol)
• medicines used to manage infection (Ex. ciprofloxacin, ofloxacin, levofloxacin moxifloxacin)
• drugs used to increase the rate of urine excretion (Ex. thiazides, furosemide, amiloride)
• medicines that stop blood clotting (anticoagulants) Ex. warfarin, heparin
• methotrexate (used to manage cancer and autoimmune disorders such as arthritis and skin conditions)
• mifepristone (medicine used for medical abortion)
• hydrocortisone, prednisolone (for the management of swelling and inflammation)
• medicines used to suppress the immune system after organ transplant (Ex. cyclosporine or tacrolimus)
• zidovudine (medicines used to manage HIV infection)
• glibenclamide, glicazide, tolbutamide (medicines used to manage diabetics)
• aspirin, ibuprofen, naproxen, celecoxib and etoricoxib (drugs used to manage pain and inflammation)
• clopidogrel (medicine used to manage blood clots)

Overdosage:

If you or anyone else accidentally take too much of DOLOWIN SR TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are low blood pressure, gastrointestinal irritation, respiratory depression and convulsions.

SYNOPSIS

MORE INFORMATION

• Keep DOLOWIN SR TABLET out of the sight and reach of children
• Store DOLOWIN SR TABLET at room temperature