INTRODUCTION ABOUT DAPARYL 10 TABLET

DAPARYL 10 TABLET is used to manage type II diabetes mellitus when diet and exercise does not result in adequate control on blood glucose levels. It is also used in the management of heart failure and chronic kidney disease (reduced kidney function). It contains Dapagliflozin which belongs to the group of medicines called Antidiabetic agents.

During therapy with DAPARYL 10 TABLET, your doctor might regularly monitor blood sugar levels and kidney functions to avoid the risk of unwanted side effects. Before taking the medicine, inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have type I diabetes, severe low blood pressure, severe dehydration or conditions which can cause dehydration (such as nausea, vomiting, fever, serious illness or any surgery).

The most common side effects are back pain, passing more urine, constipation, dizziness and rash. Consult your physician if any of these side effect worsens.

USES OF DAPARYL 10 TABLET

It is used to manage:

• Type II diabetes mellitus  
• Heart failure
• Chronic kidney disease

HOW DAPARYL 10 TABLET WORKS

DAPARYL 10 TABLET contains Dapagliflozin which works by blocking the action of a protein called SGLT-2 in the kidneys. This action manages the reabsorption of glucose and sodium ions in the kidneys. As a result, it excretes excess glucose and from the body in the form urine leading to decrease in blood sugar levels. It also protects kidney function and manages it from further damage. Additionally, it reduces the strain on the heart and helps it to pump blood more efficiently with less pressure.

DIRECTIONS FOR USE

• Take DAPARYL 10 TABLET as advised by your physician
• Swallow the medicine with a glass of water. Do not crush or chew the medicine. It can be taken with or without meals
• Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition
• Do not stop taking DAPARYL 10 TABLET unless your doctor advice you to stop

SIDE EFFECTS OF DAPARYL 10 TABLET

Common side effects of DAPARYL 10 TABLET:

• fungal infections of genital (thrush) causing itching, irritation, unusual discharge, odor
• back pain
• passing more urine, increased urine frequency
• dizziness
• skin rash
• dehydration, thirst
• constipation
• dry mouth

Stop taking DAPARYL 10 TABLET and contact your doctor immediately if you experience any of the following side effects such as:

• signs of allergic reaction (skin rash, itching, swelling of the face, tongue or throat, causing difficulty in breathing and swallowing)
• signs of diabetic ketoacidosis (nausea or vomiting, stomach pain, excessive thirst, fast and deep breathing, confusion, unusual sleepiness or tiredness, a sweet smell to breath, a sweet or metallic taste in the mouth or a different odor to urine or sweat, and rapid weight loss)
• pain, swelling, redness or tenderness of the genitals or the areas between the genitals and the anus accompanied with high fever or a feeling generally unwell (sign of necrotizing fasciitis of the perineum)
• signs of urinary tract infection (such as fever and/or chills, burning sensation while passing urine, pain in the back or side)
• bloody urine
• signs of low blood sugar levels (shaking, sweating, anxiety, hunger, fast heartbeat, headache, change in vision, mood swings, confusion)

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking the medicine, inform your doctor if you are taking any of the following medicines such as:

• diuretics (Ex. furosemide, hydrochlorothiazide)
• Antidiabetics (Ex. insulin or glimepiride, gliclazide)

Overdosage:

If you or anyone else accidentally take too much of DAPARYL 10 TABLET, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS