INTRODUCTION ABOUT CLOPITAB 150MG TABLET

CLOPITAB 150MG TABLET contains Clopidogrel which belongs to the group of medicines called Antiplatelets. CLOPITAB 150MG TABLET is used to manage blood clots (thrombi) due to atherothrombosis which may lead to atherothrombotic events such as stroke or heart attack and atherosclerotic events (myocardial infraction) in patients with atherosclerosis. It is also used to manage in-stent restenosis in patients undergo percutaneous coronary Intervention (PCI).

Platelets are very small structures in the blood which clump together during blood clotting. By managing this clumping, antiplatelet medicinal products reduce the chances of blood clots forming (a process called thrombosis).

Atherothrombosis is an inflammatory process of the arteries that affects the coronary (heart), cerebral (brain) and peripheral circulation (blood circulation to arms, hands, legs and feet) by aberrant thickening of the blood vessel wall and reducing the blood flow to the tissue that triggers the occurrence of myocardial infarction, stroke and peripheral arterial disease.

Along with this management, your doctor may advise regular blood tests to check your blood clotting time.

Avoid taking CLOPITAB 150MG TABLET, if you are allergic to Clopidogrel or have a medical condition that is currently causing bleeding such as a stomach ulcer or bleeding within the brain, severe liver disease.

Before taking CLOPITAB 150MG TABLET, inform your doctor if you are at a risk of internal bleeding, have or ever had a clot in artery of your brain (ischemic stroke) which might have occurred within the last seven days or have heart or kidney problems.

CLOPITAB 150MG TABLET is not recommended for use in pregnant and breastfeeding women. It is not recommended for use in children and adolescents (below 18 years of age). Consult your doctor before taking CLOPITAB 150MG TABLET.

The most common side effects of taking CLOPITAB 150MG TABLET are bleeding, diarrhea, abdominal pain, indigestion and heartburn. Consult your doctor if any of these above symptoms gets worse.

USES OF CLOPITAB 150MG TABLET

It is used to:

• prevent blood clots (thrombi) forming in hardened blood vessels (atherothrombosis)
• manage atherosclerotic events (myocardial infraction)
• prevent in-stent restenosis in patients undergo percutaneous coronary intervention (PCI)

HOW CLOPITAB 150MG TABLET WORKS

CLOPITAB 150MG TABLET works by managing platelets from sticking together, thereby decreasing the formation of harmful blood clots that results in the lower chance of occurrence of heart attack or stroke.

DIRECTIONS FOR USE

Take CLOPITAB 150MG TABLET as advised by your physician. Swallow CLOPITAB 150MG TABLET with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF CLOPITAB 150MG TABLET

Constipation:

Try to eat more high-fiber foods such as fresh fruit, vegetables, cereals and drink plenty of water. If this does not help, inform your doctor for receiving alternate managements for constipation.

Dizziness:

Try to rest and relax and get enough sleep. Try to avoid driving or operating any tools or machines while you are feeling dizzy. Limit your consumption of alcohol, as it can aggravate your dizziness. Consult and inform your doctor if the symptom does not improve.

Headache:

If CLOPITAB 150MG TABLET causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking CLOPITAB 150MG TABLET. If headaches last more than a week or severe, inform your doctor.

Nausea and Vomiting:

Try to take CLOPITAB 150MG TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom gets worse.

Indigestion:

Try to have smaller and more frequent meals and reduce consumption of tea, coffee, cola or alcohol and lose weight if you are obese. Avoid smoking and do not have rich, spicy or fatty foods. Consult and inform your doctor if the symptom does not improve.

Diarrhea:

Drink lots of fluids, such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to manage diarrhea and consult your doctor if the symptom gets worse.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking CLOPITAB 150MG TABLET, inform your doctor, if you are taking any of the following medicine:

• oral anticoagulants (medicines used to reduce blood clotting) such as dabigatran, rivaroxaban, apixaban
• non-steroidal anti-inflammatory drugs (medicines used to manage painful and/or inflammatory conditions of muscle or joints) such as ibuprofen, naproxen, diclofenac
• injectable medicine used to reduce blood clotting (Ex heparin, enoxaparin)
• antiplatelet agent (medicine used to manage formation of blood clot) Ex. ticlopidine
• medicines used to manage depression (Ex. fluoxetine, fluvoxamine, moclobemide)
• rifampicin (medicine used to manage severe infections)
• omeprazole or esomeprazole (medicines used to manage stomach upset)
• fluconazole or voriconazole (medicines to manage fungal infections)
• antiretroviral drugs (medicines used to manage HIV infections) Ex. efavirenz, atazanavir, darunavir, fosamprenavir
• carbamazepine (medicine to manage some forms of epilepsy)
• repaglinide (medicine used to manage diabetes)
• paclitaxel (medicine used to manage cancer)
• medicines used to manage severe pain (Ex. oxycodone, hydrocodone, codeine)

Overdosage:

If you or anyone else accidentally takes too much of CLOPITAB 150MG TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage may lead to increased risk of bleeding.

SYNOPSIS