INTRODUCTION ABOUT DOXIFLO M TABLET

DOXIFLO M TABLET is a combination of Doxofylline and Montelukast which belongs to the group of medicines called Bronchodilators and Leukotriene Receptor Antagonists respectively. It is used to manage asthma and chronic obstructive pulmonary disease (COPD).

It can also be used to reduce airway inflammation (such as bronchitis), apnea (lack of breathing), seasonal allergic rhinitis (nasal congestion, repeated sneezing, nasal itching or a red, watery and itchy eyes) and other respiratory diseases associated with bronchospasm (tightening of airways).

Before taking DOXIFLO M TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have hypertension, hyperthyroidism, stomach ulcers or any concomitant infections as a precaution.

DOXIFLO M TABLET is not recommended for use in patients with severe hypotension or heart problems (such as myocardial infarction). It is also not suitable for use in breastfeeding women.

Inform your doctor before taking DOXIFLO M TABLET if you are pregnant or planning to become pregnant. The most common side effects of taking DOXIFLO M TABLET are nausea, vomiting, upper stomach pain, headache, irritability, upper respiratory tract infections, lack of sleep, skin rash and fast heartbeat or breathing. Consult your doctor if any of these side effect worsens.

USES OF DOXIFLO M TABLET

It is used to manage and prevent:

• Asthma & COPD
• Bronchitis (inflammation of the airways)
• Apnea (breathing stops for a brief period)
• Seasonal allergic rhinitis (nasal congestion, repeated sneezing, nasal itching or a red, watery and itchy eyes)
• Exercise induced bronchospasm (narrowing of airways)

HOW DOXIFLO M TABLET WORKS

DOXIFLO M TABLET is a bronchodilator with anti-inflammatory properties. It blocks the release of certain chemicals (such as phosphodiesterase, leukotrienes) in the respiratory tract that triggers airway inflammation, swelling and narrowing. As a result, it widens the airways and reduces airway inflammation. This allows the air to pass through more freely through the airways which makes breathing easier.

DIRECTIONS FOR USE

Take DOXIFLO M TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Your doctor will decide the correct dose, duration of therapy and number of doses per day depending upon your age, body weight and disease condition.

Do not stop taking DOXIFLO M TABLET once your symptoms subside without consulting your doctor.

SIDE EFFECTS OF DOXIFLO M TABLET

HOW TO MANAGE SIDE EFFECTS

Nausea and Vomiting:

Take DOXIFLO M TABLET with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your symptom worsens.

Headache:

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug Interactions:

Before taking DOXIFLO M TABLET, inform your doctor if you are taking any of the following medicines such as:

• other methylxanthines (used to manage respiratory problems) Ex. etophylline, aminophylline
• medicines used to manage bacterial infections (such as erythromycin, troleandomycin, lincomycin, clindamycin)
• allopurinol (a medicine used to manage gout)
• cimetidine (a medicine used to manage stomach ulcers)
• influenza vaccine
• propranolol (a medicine used to manage heart problems)
• phenytoin (a medicine used to manage fits)
• sympathomimetic drugs (medicines used to increase heart rate and hypertension) Ex. ephedrine
• medicines used to manage fits (Ex. phenobarbital, phenytoin)
• rifampicin (a medicine used to manage tuberculosis)
• medicines used to relieve fever, pain and inflammation (Ex. aspirin, ibuprofen)
• gemfibrozil (a medicine used to control blood cholesterol levels)

B. Drug-Food Interactions:

Limit the consumption of foods and beverages rich in caffeine (such as coffee) while taking DOXIFLO M TABLET.

Overdosage:

If you or anyone else accidentally took more DOXIFLO M TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include stomach pain, sleepiness, thirst, headache, vomiting and hyperactivity.

SYNOPSIS

MORE INFORMATION

• Keep DOXIFLO M TABLET out of reach of children
• Store DOXIFLO M TABLET at room temperature